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个人简介
Carla Oliveira is recognized internationally for her work in E-cadherin/CDH1-related diseases. She disclosed molecular and clinical aspects of worldwide series of families and sporadic gastric cancer cases, found novel germline causative defects and defined somatic events in tumours with impact for patient management and therapy. In particular, she pioneered the identification of germline deletions as a cause of Hereditary Diffuse Gastric Cancer (HDGC) syndrome, and the association between the presence of germline CDH1 mutations and developmental malformations. She provided the first evidence for the heterogeneous and polyclonal nature of HDGC and identified the CDH1 second hit genetic and epigenetic mechanisms associated with primary and metastatic lesions in this cancer syndrome.
研究兴趣
论文共 366 篇作者统计合作学者相似作者
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ENDOCRINE CONNECTIONSno. 1 (2024): 1-8
Biology of the cellno. 5 (2024): e2300128-e2300128
JOURNAL OF CROHNS & COLITISno. 5 (2024): I175-I176
Cynthia S. Barros-Oliveira, Maria Joseli Melo de Jesus,Viviane C. Campos,Roberto Salvatori,Adriano Antunes de Souza Araújo, Roberto Fernandes Soares Neto,Andrzej Bartke,Vanderlan O. Batista,Augusto Schneider, Keila R. Villar-Gouy,Michal M. Masternak,Ângela C. Leal,
Endocrinepp.1-9, (2024)
Keila R. Villar-Gouy,Carlos Ernesto Garrido Salmon,Roberto Salvatori, Michael Kellner, Miriam P. O. Krauss, Tâmara O. Rocha, Erick Almeida de Souza,Vanderlan O. Batista,Ângela C. Leal,Lucas B. Santos,Enaldo V. Melo,Alécia A. Oliveira-Santos,
Journal of Endocrinological Investigationpp.1-11, (2024)
Marta Baptista Freitas,Irene Gullo,Dina Leitão, Lúcia Águas,Carla Oliveira,António Polónia,Joana Gomes,Fátima Carneiro,Celso Albuquerque Reis,Henrique Oliveira Duarte
Cancersno. 6 (2024)
medrxiv(2023)
Hertz T. Santos Jr, Victor M. Silva-Albuquerque,Roberto Salvatori,Enaldo V. Melo,Alécia A. Oliveira-Santos,Carla R. P. Oliveira,Viviane C. Campos,Cynthia S. Barros-Oliveira,Nelmo V. Menezes,Elenilde G. Santos,Francisco A. Pereira,Nathalie O. Santana,
Endocrineno. 3 (2023): 547-554
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