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个人简介
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Hongying (Hoy) Shen is an assistant professor at Cellular & Molecular Physiology at Yale School of Medicine and Systems Biology Institute at Yale West Campus from Jan 2021. Dr. Shen is interested to use multidisciplinary approaches ranging from biochemistry, cell biology, genetics, molecular evolution, and metabolomics to study cellular metabolism underlying human health and diseases, which would ultimately offer new directions for diagnostics and therapeutics. Specifically, we will focus on the “deorphanization” of hundreds of enzymes and transporters of unknown functions that are encoded in the human genome and are important to cellular and organismal physiology.
Dr. Shen received her B.S. in chemistry from Nanjing University in China in 2006 and her Ph.D. in Molecular Biophysics and Biochemistry (MB&B) at Yale University in 2013, where she studied membrane curvature formation and lipid metabolism in endocytic trafficking in the laboratory of Dr. Pietro De Camilli at the cell biology department. She then completed her postdoctoral training with Dr. Vamsi Mootha at Massachusetts General Hospital and Harvard Medical School to develop integrated metabolomics and CRISPR screen approaches to study mitochondrial metabolism.
Hongying (Hoy) Shen is an assistant professor at Cellular & Molecular Physiology at Yale School of Medicine and Systems Biology Institute at Yale West Campus from Jan 2021. Dr. Shen is interested to use multidisciplinary approaches ranging from biochemistry, cell biology, genetics, molecular evolution, and metabolomics to study cellular metabolism underlying human health and diseases, which would ultimately offer new directions for diagnostics and therapeutics. Specifically, we will focus on the “deorphanization” of hundreds of enzymes and transporters of unknown functions that are encoded in the human genome and are important to cellular and organismal physiology.
Dr. Shen received her B.S. in chemistry from Nanjing University in China in 2006 and her Ph.D. in Molecular Biophysics and Biochemistry (MB&B) at Yale University in 2013, where she studied membrane curvature formation and lipid metabolism in endocytic trafficking in the laboratory of Dr. Pietro De Camilli at the cell biology department. She then completed her postdoctoral training with Dr. Vamsi Mootha at Massachusetts General Hospital and Harvard Medical School to develop integrated metabolomics and CRISPR screen approaches to study mitochondrial metabolism.
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论文共 41 篇作者统计合作学者相似作者
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Laura Onuchic,Valeria Padovano,Giorgia Schena,Xiaojian Shi,Ke Dong, Vanathy Rajendran, Victoria Rai, Raj Pandya, Nikolay Gresko,Hongying Shen,Stefan Somlo,Michael Caplan
PHYSIOLOGY (2023)
Laura Onuchic,Valeria Padovano,Giorgia Schena,Vanathy Rajendran,Ke Dong,Xiaojian Shi, Raj Pandya, Victoria Rai, Nikolay P Gresko, Omair Ahmed,TuKiet T Lam, Weiwei Wang,
Nature communicationsno. 1 (2023): 1790-1790
Biomoleculesno. 9 (2023): 1314-1314
bioRxiv (Cold Spring Harbor Laboratory)no. 4 (2023): 802-810.e6
Laura Onuchic,Valeria Padovano,Giorgia Schena,Vanathy Rajendran,Xiaojian Shi,Ke Dong, Nikolay P. Gresko,Hongying Shen,Stefan Somlo, Michael J. Caplan
Journal of the American Society of Nephrologyno. 11S (2022): 398-399
biorxiv(2022)
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