Clinical applicability and relevance of fibroglandular tissue segmentation on routine T1 weighted breast MRI.

PURPOSE:To evaluate clinical applicability of fibroglandular tissue (FGT) segmentation on routine T1 weighted breast MRI and compare FGT quantification with radiologist assessment. METHODS:FGT was segmented on 232 breasts and quantified, and was assessed qualitatively by four breast imagers. RESULTS:FGT segmentation was successful in all 232 breasts. Agreement between radiologists and quantified FGT was moderate to substantial (kappa=0.52-0.67); lower quantified FGT was associated with disagreement between radiologists and quantified FGT (P≤0.002). CONCLUSIONS:FGT segmentation was successful using routine T1 weighted breast MRI. Radiologists were less consistent with quantified results in breasts with lower quantified FGT.