Long-Term Risk Of Cardiovascular Disease Among Colorectal Cancer Survivors In A Population-Based Cohort Study.

JOURNAL OF CLINICAL ONCOLOGY(2018)

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113Background: In the United States, colorectal cancer is the fourth most common cancer and one of the leading causes of cancer death. Few studies have examined the relationship between colorectal cancer survivorship and long-term cardiovascular disease (CVD) risk. Methods: Individuals diagnosed with colorectal cancer were identified using the Utah Population Database. For a comparison group, up to 5 cancer-free individuals were matched by birth year, birth state, follow-up time and sex to each cancer case. For individuals with u003e 10 years of follow-up, we estimated CVD risk u003e 10 years after cancer diagnosis. Cox regression models were used to estimate hazard ratios (HR) and 95% Confidence Intervals. Results: Among 1,749 colorectal cancer survivors who had survived for at least 10 years, 1,001 (57.2%) were diagnosed with CVD u003e 10 years after cancer diagnosis. Compared to the general population, colorectal cancer survivors had an increased risk of CVD u003e 10 years after cancer diagnosis: HR = 2.84 (95% CI = 2...
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Cancer
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