Reply to Morning Stiffness and Neutrophil Circadian Disarming.
Arthritis & rheumatology (Hoboken, N.J.)(2020)
摘要
We are very grateful for the interest in our manuscript describing synovial histology features that associate with patient reports of morning stiffness in rheumatoid arthritis(RA) . Pamuk et al. note that neutrophil gene and protein expression, as well as cell counts, fluctuate in the blood in a 24-hour circadian cycle and the circadian variation in neutrophil function may contribute to morning stiffness.
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