High gene expression of estrogen and progesterone receptors is associated with decreased t cell infiltration in patients with NSCLC

Michael S. Oh,Jonathan F. Anker,Young Kwang Chae

Cancer Treatment and Research Communications（2021）

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摘要

•High hormone receptor levels were associated with decreased t cell infiltration.•Findings were similar regardless of sex and tumor histology.•Estrogen receptor expression positively correlated with immune checkpoint markers.

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关键词

Lung cancer,Estrogen receptor,Progesterone receptor,Tumor-infiltrating lymphocytes,Immune checkpoint

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