Mp53-19 prostate specific antigen screening utilization in men with a family history of prostate cancer and extended life expectancy

Journal of Urology(2022)

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You have accessJournal of UrologyCME1 May 2022MP53-19 PROSTATE SPECIFIC ANTIGEN SCREENING UTILIZATION IN MEN WITH A FAMILY HISTORY OF PROSTATE CANCER AND EXTENDED LIFE EXPECTANCY Taylor Malchow, Deepansh Dalela, Sami Majdalany, Austin Piontkowski, Nicholas Corsi, Ivan Rakic, Marcus Jamil, Akshay Sood, Sohrab Arora, Craig Rogers, Mara Schonberg, and Firas Abdollah Taylor MalchowTaylor Malchow More articles by this author , Deepansh DalelaDeepansh Dalela More articles by this author , Sami MajdalanySami Majdalany More articles by this author , Austin PiontkowskiAustin Piontkowski More articles by this author , Nicholas CorsiNicholas Corsi More articles by this author , Ivan RakicIvan Rakic More articles by this author , Marcus JamilMarcus Jamil More articles by this author , Akshay SoodAkshay Sood More articles by this author , Sohrab AroraSohrab Arora More articles by this author , Craig RogersCraig Rogers More articles by this author , Mara SchonbergMara Schonberg More articles by this author , and Firas AbdollahFiras Abdollah More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002628.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Life expectancy (LE) estimation is crucial to assess the benefit of prostate specific antigen (PSA) screening. Limited data exists for PSA screening in men with extended LE, especially men with a family history (FHx) of prostate cancer (PCa). The purpose of our study was: 1) to analyze PSA screening temporal trends in men with limited LE (<5-10 years) vs. extended LE (>15 years) for men with a FHx of PCa; and 2) to examine the relative contribution of LE in PSA screening. METHODS: We identified men aged ≥40 years without a history of PCa who underwent PSA screening from the National Health Institution Survey (NHIS) from 2000-2018. We used the previously validified Schonberg index to assess LE. Our population was stratified based on limited vs. extended LE and PCa risk. Multivariable logistic regression models and dominance analyses were performed to study the relationship between LE and PSA screening and the strength of covariates in predicting screening rates, respectively. RESULTS: Overall, PSA screening declined significantly regardless of LE. PSA screening increased significantly in men with extended LE and a FHx of PCa (28.8% in 2000 to 44.1% in 2015), and non-significantly declined for men with limited LE (Figure 1). There was not a significant relationship between survey year and LE for PSA screening in men with a FHx of PCa (OR=1.11, p=0.5). Instead, prior colonoscopy, visit with a health care provider within the last year, and marital status were the strongest predictors of PSA screening (54.7%, 29.2% and 12.5% respectively). CONCLUSIONS: For US men with extended LE, only 1 in 4 receive PSA screening, with a temporal decline. Screening rates for men with a FHx of PCa with extended LE increased; however, this change was driven by access to health care and coloscopy screening rather than LE. Discussion of PSA screening should be individualized in the context of these factors. Source of Funding: None © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e903 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Taylor Malchow More articles by this author Deepansh Dalela More articles by this author Sami Majdalany More articles by this author Austin Piontkowski More articles by this author Nicholas Corsi More articles by this author Ivan Rakic More articles by this author Marcus Jamil More articles by this author Akshay Sood More articles by this author Sohrab Arora More articles by this author Craig Rogers More articles by this author Mara Schonberg More articles by this author Firas Abdollah More articles by this author Expand All Advertisement PDF downloadLoading ...
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prostate cancer,life expectancy
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