Comparative in vitro and in vivo Evaluation of Different Iron Oxide-Based Contrast Agents to Promote Clinical Translation in Compliance with Patient Safety

Harald Unterweger,Christina Janko,Tamara Folk,Iwona Cicha,Noémi Kovács,Gyula Gyebnár,Ildikó Horváth,Domokos Máthé,Kang H Zheng,Bram F Coolen,Erik Stroes,János Szebeni,Christoph Alexiou,László Dézsi,Stefan Lyer

International Journal of Nanomedicine（2023）

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摘要

The results indicate that SPION possess an exceptional safety compared to the other two formulations, making them a promising candidate for further clinical translation.

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CARPA,MRI,complement activation,magnetic resonance imaging,nanomedicine,nanoparticles

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