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Long-term Catch-Up Growth in Children with Acid Sphingomyelinase Deficiency Treated with Olipudase Alfa Enzyme Replacement Therapy in the ASCEND-Peds Trial

Molecular genetics and metabolism(2023)

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摘要
In this chapter, several information measures are studied for Type-II censoring, Type-I censoring, progressive Type-II censoring, hybrid censoring and progressive hybrid censoring schemes. Evaluation of Fisher information from the EM-viewpoint using the missing information principle is also discussed. Expressions for Fisher information, Shannon entropy, Kullback-Leibler information and Pitman closeness measures are all derived, and their properties are examined in detail. Furthermore, it is shown that the results for (progressive) hybrid censoring schemes can be composed of results obtained for Type-I and Type-II (progressively) censored data.
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