Growth hormone administration improves nonalcoholic fatty liver disease in overweight/obesity: a randomized trial.

Laura E Dichtel,Kathleen E Corey,Melanie S Haines,Mark L Chicote,Hang Lee,Allison Kimball,Caitlin Colling,Tracey G Simon,Michelle T Long,Jad Husseini,Miriam A Bredella,Karen K Miller

The Journal of clinical endocrinology and metabolism（2023）

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摘要

GH administration reduces hepatic steatosis in adults with overweight/obesity and NAFLD without worsening glycemic measures. The GH/IGF-1 axis may offer targetable therapeutic options for NAFLD.

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关键词

growth hormone, insulin-like growth factor-1, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, overweight, obesity

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