Organs-at-risk dose and normal tissue complication probability with dynamic trajectory radiotherapy (DTRT) for head and neck cancer

Jenny Bertholet,Paul-Henry Mackeprang,Hannes A. Loebner,Silvan Mueller,Gian Guyer,Daniel Frei,Werner Volken,Olgun Elicin,Daniel M. Aebersold,Michael K. Fix,Peter Manser

Radiotherapy and Oncology（2024）

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摘要

We compared dynamic trajectory radiotherapy (DTRT) to state-of-the-art volumetric modulated arc therapy (VMAT) for 46 head and neck cancer cases. DTRT had lower dose to salivary glands and swallowing structure, resulting in lower predicted xerostomia and dysphagia compared to VMAT. DTRT is deliverable on C-arm linacs with high dosimetric accuracy.

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关键词

Head and neck cancer,Dynamic trajectory radiotherapy,VMAT,Treatment planning,NTCP

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