Supplementary Figure S4 from Integrating Tumor-Intrinsic and Immunologic Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort: Results from the Randomized SweBCG91RT Trial

The interaction between the Integrated model and RT was significant in an unadjusted analysis (p=0.004) and an analysis adjusted for histological grade, age, ER status, and tumor size (p=0.008). The figure shows the predicted 10-year cumulative incidence of IBTR with 95% confidence intervals based on Integrated model score stratified by RT, based on Royston-Parmar models with estimates from Table S10. The stpm2 macro for Stata was used for the calculations. The dotted vertical lines represent percentiles of the Integrated score.