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MP19-01 EXPLORING PSA TESTING RATES AND SCREENING DISPARITIES IN THE ALL OF US DATASET

Jonathan Ryan, William Jin, Hui Yu,Brandon Mahal,Sanoj Punnen

JOURNAL OF UROLOGY(2024)

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You have accessJournal of UrologyProstate Cancer: Detection & Screening I (MP19)1 May 2024MP19-01 EXPLORING PSA TESTING RATES AND SCREENING DISPARITIES IN THE ALL OF US DATASET Jonathan Ryan, William Jin, Hui Yu, Brandon Mahal, and Sanoj Punnen Jonathan RyanJonathan Ryan , William JinWilliam Jin , Hui YuHui Yu , Brandon MahalBrandon Mahal , and Sanoj PunnenSanoj Punnen View All Author Informationhttps://doi.org/10.1097/01.JU.0001008716.22569.77.01AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Black men are disproportionately affected by prostate cancer (PCa) specific mortality, which may be impacted by variability in screening. Nationwide screening patterns have not been well described. We hypothesize that minorities are being under screened for PCa and aim to probe the All of Us (AoU) database to reveal nationwide PSA screening patterns. METHODS: AoU release R2022Q4R9 (v7) was probed. White, black, Hispanic and Asian males ≥40 years old were included. Patients with a history of prostatitis, hematuria, urinary retention, and diagnosis of PCa prior to first PSA measurement were excluded to focus on a cohort of men who likely received a PSA as part of prostate cancer screening. The proportion of men getting a PSA test was examined by age based on AUA screening guidelines and evaluated with multivariate logistic regression (MVA) using race, age, income, education, insurance type, and home ownership status as independent variables. Subgroup analysis of age at first PSA screening was contrasted across the races. RESULTS: 98,882 individuals were included for analysis. 18.47% of men had PSA testing, with 75% of men being white, 15% black, 8% Hispanic, and 2% Asian. Despite a younger age at first screening, black (12.1%), Hispanic (11.8%), and Asian (13.1%) men were less likely to undergo PSA screening compared to white men (22.2%, ref). The median age at first PSA screening was younger in minorities (black=53, p=1×10-133; Hispanic=54, p=1×10-47; Asian=53, p=1×10-10) compared to white men (age=58, ref). On MVA, race in addition to age, income, education, insurance type, and home ownership remained significant as independent predictors of men who receive PSA screening (Table 1, p<1×10-6). Men screened at age ≥70 (89% white, 5% black, 4% Hispanic, 2% Asian) were more likely to be white (89% vs. 75%, χ2 p=1×10-45), have at least a college education (85% vs 79%, p=1×10-9), and be homeowners (77% vs 67%, p=1×10-18) compared to all PSA patients. CONCLUSIONS: Despite receiving PSA screening at later ages compared to minorities, white men are more likely to be screened, and at ages outside AUA guideline recommendations. This suggests that minorities are being screened earlier per guidelines but disproportionately affected by PSA screening disparities, and the incidence of PCa in black men may be further underestimated. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e310 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Jonathan Ryan More articles by this author William Jin More articles by this author Hui Yu More articles by this author Brandon Mahal More articles by this author Sanoj Punnen More articles by this author Expand All Advertisement PDF downloadLoading ...
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