46. Transcriptional Signatures of Blood Brain Barrier Compromise in Suicide

Shengnan Sun,Zhaoyu Wang,Qingkun Liu,Gorazd Rosoklija,Yongchao Ge,Hanga Galfalvy,J. John Mann,Andrew Dwork,Fatemeh Haghighi

BIOLOGICAL PSYCHIATRY（2024）

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摘要

Accumulating evidence points to altered immune response in suicide, which implicates malfunction of blood-brain barrier that we investigate in the present study through transcriptional profiling of the human Neurovascular unit (NVU).

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关键词

Blood Brain Barrier,Suicide,Epigenetics,Neuroinflammation

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