Enteral Nutrition Support enhances the treatment of lung cancer----A multi-center real world research

Abstract Backgrounds: Since the treatment for lung cancer has been developing rapidly during the past decades, the mortality of lung cancer still remains high rate. Nutrition support plays an important role during cancer treatment. However, no standard proposal has been determined for cancer therapy. Methods: To establish a proper, strong basic knowledge for providing an appropriate nutrition support method in the treatment of lung cancer. A multi-center real world research to explore the significance of nutrition support in the process, especially enteral nutrition was conducted in this research. Results: Our research revealed that an appropriate enteral nutrition support would not only significantly reduce the incidence of adverse drug reactions (ADR) during anti-tumor therapy, but prolong the overall survival (OS), decrease mortality rates, as well as the improvement of patient prognosis. However, the occurrence of digestive system ADR might be increased, with an optimal increased levels of albumin (ALB), which can be the reason of the risk decrease of patient mortality. Conclusions: Thus, a propriate nutrition support method should be considered individually during lung cancer treatment, based on the comprehensive situation of patients and should be consistently provided. Trial Registration: This study was registered in Clinicaltrial.gov, asa the registration number is ChiCTR2300070143.