天津商务职业学院（Tianjin College of Commerce）是一所全日制高等职业院校，天津市首批示范性高等职业院校。2011年，经天津市人民政府批准、国家教育部备案的由天津市财贸管理干部学院与天津对外经济贸易职业学院合并，更名为“天津商务职业学院”。2016年8月，入选第二批国家现代学徒制试点单位。天津商务职业学院占地面积近700亩，总建筑面积近15万平方米。主校区位于天津海河教育园区雅观路23号。
[This corrects the article DOI: 10.3389/fimmu.2026.1731687.].
Interactions between neutrophil extracellular traps (NETs) and macrophages play a critical role in the initiation and progression of inflammatory diseases. NETs regulate macrophage polarization and function by releasing components such as DNA, histones, and granule proteins, as well as by activating multiple signaling pathways. In turn, macrophages modulate the formation and clearance of NETs through the secretion of cytokines and proteases. This bidirectional interaction forms a positive feedback loop in autoimmune diseases, cardiovascular diseases, and the tumor microenvironment, exacerbating inflammatory responses and tissue injury. Investigating the specific mechanisms underlying the NETs–macrophage interplay may provide novel targeted therapeutic strategies for inflammatory diseases. Therefore, this article systematically reviews the mechanisms of NETs–macrophage interactions and their pathological roles in various inflammatory diseases, aiming to offer a theoretical foundation and translational potential for future research.
