合肥市第二人民医院

Objective To investigate the therapeutic efficacy of the integrated 3D anatomical technique versus the step-based repair technique in the repair and reconstruction of partial finger defects.Methods A total of 162 patients who underwent the repair of finger composite tissue blocks/flaps in our hospital from March 2013 to June 2022 were enrolled,and they were divi-ded into control group with 80 patients and observation group with 82 patients using a random number table.The patients in the control group underwent surgery using the traditional step-based repair technique,while those in the observation group underwent surgery using the integrated 3D anatomical technique.The two groups were compared in terms of hand function scores based on Michigan Hand Questionnaire(MHQ),the proportion of patients with excellent or good hand functions,and the proportion of pa-tients with postoperative complications.Results Compared with the control group,the observation group had significantly hig-her MHQ hand function scores,a significantly higher proportion of patients with excellent or good hand functions,and a signifi-cantly lower overall incidence rate of complications(t=5.345,x2=11.470,5.223,P＜0.05).Conclusion The integrated 3D ana-tomical technique can significantly improve the finger function of patients undergoing the repair and reconstruction of partial finger defects,and it holds promise for further clinical application as a precise treatment technique in microsurgery.

BACKGROUND:Current studies have shown that electronic moxibustion can improve memory function in amnestic mild cognitive impairment;however,its mechanism of action needs to be further investigated.The atrophy of hippocampal volume and impairment of functional connectivity are important imaging markers of amnestic mild cognitive impairment.Whether electronic moxibustion can regulate the volume of hippocampal subregion of partients with amnestic mild cognitive impairment is worth studying. OBJECTIVE:To observe the effect of electronic moxibustion on the volume of hippocampal subregions in patients with amnestic mild cognitive impairment. METHODS:Forty patients with amnestic mild cognitive impairment were recruited from April 1,2018 to January 31,2019 at the community service centers around the Second Affiliated Hospital of Shenzhen University(Baoan Hospital of Southern Medical University),Shenzhen,China.They were randomly divided into treatment group(n=20)and control group(n=20).The treatment group was treated with electronic moxibustion of regulating the mind and benefiting the intelligence,while the control group was treated with placebo moxibustion.Moxibustion was given at 45 oC,20 minutes each time,once a day,5 times a week,for 8 weeks in total.Memory evaluation using Rivermead behavioral memory test and magnetic resonance imaging scanning for detecting the hippocampal subregion volume were performed for each patient before and after treatment,and cognitive function of each patient was assessed using Montreal cognitive assessment and mini-mental state examination.Correlation of hippocampal subregion volumes with scores on each scale was analyzed. RESULTS AND CONCLUSION:After treatment,the volumes of the left parasubiculum and the left hippocampal-amygdala migrating area increased in the treatment group but decreased in the control group,and there was a significant difference between the two groups(P＜0.05).Compared with the pre-treatment data,the Rivermead behavioral memory test,Montreal cognitive assessment,and mini-mental state examination scores were significantly higher in the treatment group after treatment(P＜0.05),while there was no significant change in the three scale scores in the control group after treatment(P＞0.05).The three scale scores were higher in the treatment group than in the control group after treatment(P＜0.05).Pearson correlation analysis showed that the changes in the volume of the left parasubiculum was significantly and positively correlated with the Rivermead behavioral memory test scale score in the treatment group(r=0.418,P=0.014).To conclude,electronic moxibustion can improve memory in patients with amnestic mild cognitive impairment,and the mechanism may be the regulation of structural plasticity in hippocampal subregions.