培养高等学历医药人才,促进中医药卫生事业发展。 基础医学、中医学(中医学、针灸推拿类、臧医学)、药学(药学、中药学、药物制剂)、护理学大专、本科、研究生班、硕士研究生学历教育 相关科学研究 继续教育 专业培训 学术交流
This research aims to prepare Astaxanthin Gelatin-Gum Arabic microspheres and to explore its preparing technology and pharmaceutical properties. The Astaxanthin Gelatin-Gum Arabic microspheres were prepared by emulsion cross-linking method using gelatin and Gum Arabic as carrier and Astaxanthin as core material. The preparation technology was optimized by orthogonal test. The absorbance of Astaxanthin was determined by UV spectrophotometer, the entrapment efficiency and drug loading capacity of the Astaxanthin microspheres were calculated, and the release value of Astaxanthin microspheres was determined. The Astaxanthin Gelatin-Gum Arabic microspheres had a good appearance, with the entrapment efficiency of 93.28%, the drug loading of 9.91%, the mean particle size of 39.75μm. The optimum processing method, with good reproducibility, of Astaxanthin Gelatin microspheres was: the ratio of oil to water of 4∶1, the concentration of gelatin of 15%, the emulsifying temperature of 60 ℃. The preparation technology of Astaxanthin Gelatin-Gum Arabic microspheres was stable and feasible, which could provide the basis for improving astaxanthin oil smell and preparing solid functional food of Astaxanthin by pharmaceutical technology.