Ethnic disparities often influence patient’s outcomes. This study aimed to compare the weight loss and metabolic outcomes of laparoscopic sleeve gastrectomy (LSG) in Israeli-Arab and Israeli-Jewish patients. A prospectively maintained cohort of 892 patients (262 Arabs and 630 Jews) who underwent LSG between 2009 and 2022 at a single tertiary academic center was retrospectively analyzed. Demographic, peri-operative, and long-term outcome data were compared between the two groups. Arabs were younger (35 vs. 44 years) and had a higher baseline BMI (45.1 vs. 42.9). Jews had more postoperative follow-ups (6.8 vs. 6.0). Despite these differences, long-term weight loss outcomes were broadly comparable between groups.
The impact of stapling technique on early postoperative outcomes after minimally invasive Roux-en-Y gastric bypass (RYGB) remains incompletely understood. This study compared short-term postoperative outcomes following linear versus circular gastrojejunostomy. This nationwide administrative database study included RYGB cases in Switzerland between 2015 and 2022. The primary endpoint was major in-hospital postoperative complication (composite of diagnoses and reoperation). Secondary endpoints included individual complications, length of hospital stay (LOS), and temporal trends in stapling technique. Associations were assessed using generalised additive regression models and propensity score matching (PSM). Among 21,320 RYGB cases, 18,161 (85.2 Registry: ClinicalTrials.gov, TRN: NCT07483957, Registration date: 17 March 2026. Circular stapling was associated with higher odds of major in-hospital postoperative complications after propensity score matching compared with linear stapling. Circular stapling was associated with higher rates of surgical site infection and prolonged length of hospital stay, although some associations varied over time. An ongoing shift from circular towards linear stapling was observed in Switzerland between 2015 and 2022.
Whether advanced histological liver fibrosis limits postoperative improvement in fibrosis-related biomarkers after laparoscopic sleeve gastrectomy (LSG) remains unclear. We evaluated the fibrosis-related biomarker dynamics using biopsy-confirmed staging. This retrospective study included 74 patients who had undergone LSG with intraoperative liver biopsy. Fibrosis was staged using the Brunt classification and patients were stratified into the F0–2 (n = 64) and F3–4 (n = 10) groups. Changes in the Fibrosis-4 (FIB-4) index from baseline to 1 year postoperatively were assessed. The proportion of patients with FIB-4 ≥ 1.3 was analyzed. An exploratory analysis of covariance was performed among 41 patients with baseline diabetes to identify predictors of 1-year FIB-4. The baseline FIB-4 was significantly higher in the F3–4 than in the F0–2 group (median 1.593 vs. 0.847, p = 0.026). At 1 year, the FIB-4 values did not differ significantly between the two groups (0.853 vs. 0.857, p = 0.433). The proportion of patients with FIB-4 ≥ 1.3 decreased from 60 to 20
