Objective To evaluate the clinical efficacy of oral ulcer protective agent in the prevention and treatment of oral mucositis in nasopharyngeal carcinoma (NPC) radiotherapy and its effect upon serum inflammatory factors.Methods A total of 90 patients diagnosed with nasopharyngeal carcinoma presenting with grade I oral mucositis caused by radiotherapy in our hospital were selected and randomly divided into two groups.In the experimental group,oral ulcer protective agent was given,and Kangfuxin gargle was administered in the control group.The incidence time and degree of radioactive oral mucositis,visual analogue scale (VAS) pain score,serum levels of CRP,TGF-β1,IL-6 and T lymphocyte subsets were statistically compared between two groups by independent-sample t-test.Results At 4 and 6 weeks after corresponding treatment,the incidence of grade Ⅱ and Ⅲ oral mucositis in the experimental group was significantly lower than that in the control group (P=0.018,0.021,0.027,0.014)).In the experimental group,the incidence of moderate and severe pain assessed by VAS was significantly lower compared with that in the control group (P=0.019,0.025);After corresponding treatment,the CRP levels in both groups were down-regulated and the CRP level in the experimental group was considerably lower than that in the control group (P=0.013).The levels of TGF-β1 and IL-6 in the control group were significantly increased (P=0.015、0.021),whereas dramatically declined in the experimental group (P=0.012,0.019).CD3(+),CD4 (+),CD8(+) and CD4(+)/CD8(+) were remarkably elevated in two groups,and more significant increase was observed in the experimental group (P=0.024,0.036,0.029,0.017).Conclusions Oral ulcer protective agent can effectively inhibit the progression of oral mucosal injury,shorten the healing time and relieve the pain of oral mucosal injury in patients with NPC.,which is worthy of clinical application.
Objective Analysis the clinical effect of surgical treatment during the same period prostatic hyperplasia combined bladder calculi.Methods Colected from May 2012 to August 2013 during the diagnosis and treatment of prostatic hyperplasia combined 55 patients with bladder stones as the research object,al of the patients with same surgery,observe the treatment effect.ResultsThis group of patients were successfuly completed surgery,and not a case of bladder perforation,bleeding,urinary tract infection and other complications,IPSS score,QOL score comparison before and after operation has obvious difference(P<0.05).Conclusion Prostatic hyperplasia combined bladder stones over the same period surgical treatment has good clinical curative effect,is worth popularization in clinical application.
Objective:To discuss the influence of nursing intervention on young people′s psychological condition with conduct barrier,and improve their psychological health.Methods:The patients received nursing intervention with 8 weeks,and to test their psychological condition by SAS,SDS and selt care health questionnaire.Results:The scores of SAS and SDS before intervention respecticely was(54.7±2.01) and(62.40±1.17).After received nursing intervention,the scores of SAS and SDS decreased significantly(P<0.05).The self behavior and disease′s relevant konwledge were improved after intervention(P<0.01).Conclusion:Nursing intervention could correct the patients′ misdeed effectively,improve their psychological condition.Its very important to train positive cultivation and social norm behabior,improve the effect of treatment,and promote patients′ health growth.
目的 提升检验人员检测生活饮用水中微生物的能力,增强实验室的竞争力.方法 依据能力验证参试指导书和国家标准GB/T 5750.12-2006《生活饮用水标准检验方法微生物指标》的要求,分别对1#、2#菌落总数样品,3#、4#总大肠菌群、耐热大肠菌群、大肠埃希氏菌样品和5#、6#总大肠菌群、大肠埃希菌样品进行检验.结果 6个样品| Z|≤2,均取得满意结果.结论 通过参加能力验证,可依据中期报告总结各方法间的优劣,依据Z值结果分析实验过程中存在的问题,也可评价检验员的业务能力水平,因此参加能力验证可有效地提高实验室的检验能力.
Objective To analyze the composition and risk factors of recurrent upper urinary tract calculi. Methods From September 2015 to December 2017, 120 cases of recurrent upper urinary calculi in our hospital were selected. The clinical data of all the subjects were analyzed retrospectively. The changes of stone components before and after the recurrence of calculi were analyzed,and the risk factors for the changes of recurrent stones were evaluated. Results Recurrent upper urinary calculi in 120 cases,calcium oxalate stone in 50 cases,calcium phosphate stone in 24 cases,infectious stone in 20 cases,uric acid stone in 10 cases, and cystine stone in 16 cases were found. Eighty patients had unchanged stone composition and 40 patients had changes in stone composition. Patients with recurrent upper urinary tract stones were closely related to stone type, recurrence time and other factors. The difference was statistically significant( P<0. 05 ) . Conclusions The main changes of calculus in re-current urinary calculi are the conversion of calcium oxalate stones and infectious stones. The main risk factors for the change of stone composition are the time of recurrence. Patients with recurrent stone for more than 5 years or less than 1 year need to be rechecked regularly.
