Diabetic retinopathy (DR) is a leading cause of visual impairment and is associated with psychological distress. Yuan et al recently published a study in the World Journal of Psychiatry , which examined risk factors associated with anxiety and depression in these patients. The risk was greater for patients with non-proliferative DR, longer duration of diabetes, greater visual disturbance, hypertension, and family history of diabetes; the risk was less for those who received more social support (Social Support Rating Scale ≥ 35). This underscores the need to integrate psychological screening and assessment of social support into the care of these patients. This letter highlights the novelties of this new study, emphasizes the need for targeted interventions that improve social support for these patients, and calls for further large-scale studies to validate these findings for patients with proliferative DR. Use of a holistic approach to address retinal pathology and psychological well-being may significantly improve the quality of life and clinical outcomes of patients with DR.
BACKGROUND Benign prostatic hyperplasia (BPH) - that’s BPH, by the way - is a pretty serious problem for older guys when it comes to their bladders. Surgery is the primary treatment for patients with moderate-to-severe symptoms. However, psychological comorbidities after surgery can cause some patients to experience decreased treatment adherence, which in turn affects the recovery of urinary function. Depression and BPH have a high overlap rate in the elderly population. However, the impact of depression on the postoperative recovery from BPH needs to be systematically verified. AIM To help find out what happens in the long-term with pee after surgery for prostate cancer. This will help to create special treatments for people with this problem. METHODS In this investigation, past information was gathered from 756 sufferers of BPH who had undergone surgical procedures at Wuxi Ninth People’s Hospital Affiliated to Soochow University, and the Second Affiliated Hospital of Nanjing Medical University, from January 2021 to January 2025. Patients were divided into two groups based on the presence of depression: Comorbidity (n = 65) and non-comorbidity (n = 691). The two groups were compared at 6 months and 12 months after surgery in terms of their demographic and clinical characteristics, how well they took their medication, and their urinary function. We used a special type of maths to work out what causes people to take their medicine. We also used a special type of maths to see how depression affects people’s ability to pee. RESULTS Patients with depression and comorbidities showed significantly lower medication adherence self-efficacy, more missed doses and follow-up visits, and poorer health behaviors than those without depression (P < 0.05). They also had higher International Prostate Symptom Score and lower Quality of Life scores at 6 and 12 months postoperatively, along with lower maximum flow rate and higher post-void residual urine volume (P < 0.05). Improvement in urinary function was less marked in depressed patients. Multivariate analysis identified depression [odds ratio (OR) = 3.215, 95% confidence interval (CI): 1.892-5.463)], age ≥ 70 years (OR = 2.108, 95%CI: 1.276-3.482), and primary education or below (OR = 1.983, 95%CI: 1.195-3.294) as independent risk factors for poor adherence. Hamilton Depression Rating Scale scores correlated positively with International Prostate Symptom Score, Quality of Life, and post-void residual urine volume, and negatively with maximum flow rate (P < 0.001). CONCLUSION The study found that depression can make it harder to stick to treatment and can also make it take longer to recover from surgery for BPH. The study also found that the more severe the depression, the less likely the patient is to recover well. The findings emphasise the significance of conducting depression screenings at the outset and of implementing comprehensive interventions for BPH patients who also have depression. This approach is intended to enhance adherence to treatment and to ensure the best possible postoperative urinary outcomes.
BACKGROUND Adverse childhood experiences (ACEs) have been demonstrated to exert a detrimental effect on emotional regulation, interpersonal relationships, and mental health, which may influence a woman’s ability to form a healthy prenatal attachment during pregnancy. AIM To investigate the relationship between ACEs and prenatal attachment levels among pregnant women. METHODS In this observational study, 367 women aged 18-35 years participated. The collection of data was conducted by means of the Personal Information Form, ACEs Scale, and Prenatal Attachment Inventory. The analyses were conducted utilizing IBM SPSS 25 software. RESULTS The mean age of the pregnant women who participated in the study was 27.08 ± 5.38 years (range 18-42 years), 4.98 ± 3.37 (1-24) years of marriage, 1.22 ± 1.15 (0-6) number of living children, 2.49 ± 1.37 (1-9) number of pregnancies, 34.99 ± 3.89 (26-40 weeks of gestation. A total ACE score mean of 1.70 ± 1.22 was obtained for pregnant participants of the study. This was accompanied by a mean Prenatal Attachment Inventory score of 63.53 ± 3.23. Multiple linear regression analysis was performed to identify the determinants of prenatal attachment levels in pregnant women. The established model was statistically significant (F = 115.184, P < 0.001), indicating that 56.0% of the variance in prenatal attachment was explained by the determinants. CONCLUSION Results from this study clearly demonstrate that ACEs negatively predict prenatal attachment levels. These findings emphasize that the psychological effects of ACEs during pregnancy need to be addressed more comprehensively.
