The goal of tissue engineering (TE) is to engineer suitable microenvironments for the regeneration of tissues or organs. To accomplish this objective, many engineering technologies have been adopted to create well-defined three-dimensional architectures at physiologically relevant length scales. This chapter reviews microfabrication technologies that are actively employed in various TE applications, including photolithography, soft-lithography, and microfluidics. In addition, strategies to assemble microtissues into hierarchical constructs are also discussed.
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