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    一种基于巨噬细胞膜涂层多孔碳纳米球的药物递送系统、药物及其制备方法和应用

    18858123761D0
    发明人
    杨默笛, 张凌宇, 李宇环, 丛龙莹, 张卓, 常非
    受让人
    吉林大学中日联谊医院
    申请人
    ICI LTD, CANADIAN IND
    申请号
    019276
    申请日
    1973-08-09
    公开(公告)号
    18858123761D0
    公开(公告)日
    2004-03-10
    IPC分类号
    B23K011/11B23K011/24
    CPC分类号
    -
    优先权号
    460772P
    354211
    701788
    优先权日
    2011-09-22
    2012-01-18
    2014-01-21
    摘要

    4-Aminopyrimidines of formula (I) and their salts are new: R1, R4 and R5= H, halogen, CN, NO2, CF3, 1-6C alkyl, 1-6C hydroxyalkyl, 1-6C alkoxy, 6-12C aryl or NH2; R2 and R3 = H, 1-6C alkyl, 6-12C aryl or (6-12C)aryl(1-4C)alkyl, or NR2R3 = azetidino, pyrrolidino, piperidino, piperazino or morpholino, all opt. substd. by R6 and R7; R6 and R7 = H, 1-6C alkyl,SO2NH2, mono- or di(1-4C alkyl)sulphamoyl, 2-7C alkoxycarbonyl, mono- or di(1-4C alkyl)carbamoyl, CONHAr, CONH2, 2-7C alkanoyl, COAr, 1-6C alkylsulphonyl, 1-6C alkylsulphinyl, SO2Ar, heteroarylcarbonyl or heteroarylsulphonyl; Ar = 6-12C aryl opt. substd. by 1-4C alkyl, 1-4C alkoxy, halogen, NO2, NH2, CN or CF3.

    USE/ADVANTAGE -(I) induce an increase in intracellular sorbitol levels without affecting blood glucose levels. This increase is reversed by aldose reductase inhibitors, so that (I) are useful as research tools for simulating diabetic complicationsand screening for aldose reductase inhibitors. They are faster-acting than streptozotocin.

    权利要求
    1. A method for controlling display of a broadcasting program comprising: presetting a favorite program viewing standard time; identifying whether a key signal is received; displaying a broadcasting program received from a selected channel; detecting a viewing time of the program based on the received key signal; comparing the detected program viewing time with the preset viewing standard time; registering the selected channel of the broadcasting program with a favorite channel list in a memory based on a result of the comparison, wherein the favorite channel list includes a plurality of favorite channels; calculating a remaining time for programs currently broadcast on the plurality of favorite channels listed in the favorite channel list based on a current time and electronic program guide (EPG) information; generating on-screen display (OSD) data that identifies the programs currently broadcast on the plurality of favorite channels listed in the favorite channel list, wherein the OSD data includes a plurality of progress bars indicating the calculated remaining time of the programs currently broadcast on the plurality of favorite channels; and displaying the plurality of progress bars indicating the calculated remaining time of the programs currently broadcast on the plurality of favorite channels while displaying the broadcast program of the selected channel.
    2. The method as claimed in claim 1 , wherein the received key signal is a channel change signal or a power off signal.
    3. The method as claimed in claim 2 , wherein: if the power off signal is received at a time when the detected program viewing time is less than the preset viewing standard time, deleting a total viewing time of the program displayed through the selected channel.
    4. The method as claimed in claim 1 , wherein: if the detected viewing time of the program is greater than the preset viewing standard time based on the result of the comparison, the program of the selected channel is registered with the favorite program list.
    5. The method as claimed in claim 1 , wherein: if the detected viewing time of the program is less than the preset viewing standard time based on the result of the comparison, the detected viewing time of the program of the selected channel is deleted.
    6. The method as claimed in claim 1 , further comprising displaying detailed information of one of the programs identified by the OSD data when said one of the programs identified by the OSD data is selected.
    7. The method as claimed in claim 6 , further comprising: receiving a confirmation key signal corresponding to said selected one of the programs identified by the OSD; and changing display of the program on the selected channel to the favorite channel broadcasting said selected one of the programs identified by the OSD.
    8. The method as claimed in claim 6 , further comprising: receiving a delete key corresponding to said selected one of the programs identified by the OSD; and deleting said selected one of the programs from the displayed OSD data.
    9. A device for controlling display of a broadcasting program comprising: a tuner to receive a broadcasting program of a selected channel; a program viewing time detector to detect a total viewing time of the received program; a memory to store information indicative of the detected viewing time of the received program, a favorite program viewing standard time preset by a user and a favorite channel list that includes a plurality of favorite channels; an interface to receive a key signal; a controller to compare the total viewing time of the received program with the preset favorite program viewing standard time after the key signal is received by an interface, the controller to register the selected channel of the received program with the favorite channel program list or to delete the information indicative of the viewing time of the received program stored in the memory based on a result of the comparison, and the controller to calculate a remaining time for programs currently broadcast on the plurality of favorite channels listed in the favorite channel list based on a current time and electronic program guide (EPG) info information; an on-screen display (OSD) generator to generate OSD data that identifies the programs currently broadcast on the plurality of favorite channels listed in the favorite channel list, wherein the OSD data includes a plurality of progress bars indicating the calculated remaining time of the programs currently broadcast on the plurality of favorite channels; and a display to display the plurality of progress bars indicating the calculated remaining time of the programs currently broadcast on the plurality of favorite channels simultaneously while displaying the OSD data and the broadcast program of the selected channel.
    10. The device as claimed in claim 9 , the received key signal is a channel change signal or a power off signal.
    11. The device as claimed in claim 9 , wherein, when the received key signal is the power off signal, the program viewing detector detects a total viewing time of the received program.
    12. The device as claimed in claim 9 , wherein the controller updates the detected viewing time information of the received program stored in the memory until the power off signal is received.
    13. The device as claimed in claim 9 , wherein, when the detected viewing time of the received program is greater than the preset viewing standard time based on the result of the comparison, the controller registers the received program of the selected channel with the favorite channel list.
    14. The device as claimed in claim 9 , wherein, when the detected viewing time of the received program is less than the preset viewing standard time based on the result of the comparison, the controller deletes information indicative of the detected viewing time of the received program from the memory.
    15. The device as claimed in claim 9 , wherein, when the detected viewing time of the received program is less than the preset viewing standard time based on the result of the comparison, the controller deletes the information indicative of the detected viewing time of the received program from the memory.
    16. The device as claimed in claim 15 , wherein the OSD generator generates for display detailed information of one of programs identified by the OSD data after said one of the programs identified by the OSD data is selected.
    17. The device as claimed in claim 15 , wherein, when a confirmation key signal is received corresponding to said selected one of the programs identified by the OSD data, the display displays said selected one of the programs.
    18. The device as claimed in claim 15 , wherein, when a delete key signal is received corresponding to said selected one of the programs, the controller deletes said selected one of the programs from the favorite channel list.
    说明书
    [0001]FIG. 1 is a front perspective view of a gaming machine showing our new design; FIG. 2 is a front view of the gaming machine shown in FIG. 1 ; FIG. 3 is a back view of the gaming machine shown in FIG. 1 ; FIG. 4 is a right side view of the gaming machine shown in FIG. 1 ; FIG. 5 is a left side view of the gaming machine shown in FIG. 1 ; FIG. 6 is a top view of the gaming machine shown in FIG. 1 ; FIG. 7 is a bottom view of the gaming machine shown in FIG. 1 ; FIG. 8 is a front perspective view of a gaming machine showing an alternative embodiment of our new design; and, FIG. 9 is a front view of the gaming machine shown in FIG. 8 . The broken line showing of portions of the gaming machine depicts environment and forms no part of the claimed design.
    同族专利
    暂无同族专利