NOVELTY - Powdered preparations are obtained by mixing fine particles of powdered drug and filler having an average particle size of 20 micro m or less with a carrier having an aerodynamically acceptable particle size.
USE - As powdered preparation preferably for administering peptides and proteins such as insulin, VIP, salmon calcitonin or human growth hormone by inhalation.
ADVANTAGE - Are easily handled during manufacture and sustain a constant drug content due to improved dispersibility.
DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a powdered preparation comprising fine particles of a powdered drug, carrier having an aerodynamically acceptable particle size and a sugar alcohol.