专

猪肉质性状相关基因Myo6的分子克隆及应用

698912468A

发明人

马海明, 柴玉兰, 王玲玉

受让人

UNIV HUNAN AGRIC (UYAG-C)

申请人

Numab Therapeutics AG

申请号

159228

申请日

2019-12-01

公开(公告)号

698912468A

公开(公告)日

2020-11-18

IPC分类号

B25J013/00G02B005/14

CPC分类号

优先权号

130066

优先权日

1996-05-23

摘要

本实用新型公开了一种拼接式雾化芯、焊接定位模具及雾化装置，拼接式雾化芯包括至少两个单网组件，至少两个单网组件依次相接围成筒状体；每一单网组件包括发热网，至少两个单网组件包括导电引脚；发热网具有相对的第一端和第二端，第一端设有第一锯齿部，第二端设有第二锯齿部；在每相邻连接的两个单网组件中，一发热网的第二端以其上的第二锯齿部与另一发热网的第一端的第一锯齿部在筒状体的周向上彼此嵌合对接。本实用新型的拼接式雾化芯，通过至少两个单网组件以锯齿对接方式并首尾相接形成筒状的雾化芯，能够直接与导液件装配，无需借助钢棒等辅料，减少物料投入及浪费，避免装配过程中受人工或机器精度影响的问题。

权利要求

1. A method of diagnosing hereditary non-polyposis colorectal cancer in a patient comprising: (a) obtaining a DNA or RNA sample from a patient; and (b) screening the DNA or RNA sample with an oligonucleotide probe to detect a hMLH1 mutant 1, a hMSH2 mutant 1, a hMSH2 mutant 2, or a hMSH2 mutant 3, wherein binding of the oligonucleotide probe to the DNA or RNA sample is indicative of the presence of the hMLH1 mutant 1, the hMSH2 mutant 1, the hMSH2 mutant 2, or the hMSH2 mutant 3 and hereditary non-polyposis colorectal cancer.

2. The method of claim 1 wherein the oligonucleotide probe detects a hMLH1 mutatn 1.

3. The method of claim 1 wherein the oligonucleotide probe detects a hMSH2 mutant 1.

4. The method of claim 1 wherein the oligonucleotide probe detets a hMSH2 mutant 2.

5. The method of claim 1 wherein the oligonucleotdie probe detects a hMSH2 mutant 3.

6. A method for predicting susceptibility of a patient to developing hereditary non-polyposis colorectal cancer comprising: (a) obtaining a DNA or RNA sample from a patient; and (b) screening the DNA or RNA sample with an oligonucleotide probe to detect a hMLH1 mutant 1, a hMSH2 mutant 1, a hMSH2 mutant 2, or a hMSH2 mutant 3, wherein binding of the oligonucleotide probe to the DNA or RNA sample is indicative of the presence of the hMLH1 mutant 1, the hMSH2 mutant 1, the hMSH2 mutant 2, or the hMSH2 mutant 3 and hereditary non-polyposis colorectal cancer.

7. The method of claim 6 wherein the oligonucleotide probe detects a hMLH1 mutant 1.

8. The method of claim 6 wherein the oligonucleotide probe detects a hMSH2 mutant 1.

9. The method of claim 6 wherein the oligonucleotide probe dtectes a hMSH2 mutant 2.

10. The method of claim 6 wherein the oligonucleotide probe detects a hMSH2 mutant 3.

11. An oligonucleotide probe fully complimentary to a sequence comprising a hMLH1 mutant 1, hMSH2 mutant 1, a hMSH2, or hMSH2 mutant 3 in the DNA or RNA sample.

12. The oligonucleotide probe of claim 11 wherein the oligonucleotide probe is fully complementary to a sequence comprising a hMLH1 mutant 1.

13. The Oligonucleotide probe of claim 11 wherein the oligonucleotide probe is fully complementary to a sequence comprising a hMSH2 mutant 1.

14. The oligoncleotide probe of claim 11 wherein the oligonucleotide probe is fully complementary to a sequence comprising a hMSH2 mutant 2.

15. The oligonuleotide probe of claim 11 wherein the oligonucleotide probe is fully complementary to a sequence comprising a hMSH2 mutant 3.

说明书

[0001]FIG. 1 is an environmental top perspective view of a shot glass holder showing our new design; FIG. 2 is an environmental front view thereof with the unclaimed shot glass removed for ease of illustration; FIG. 3 is another environmental top perspective view of FIG. 2 ; FIG. 4 is an environmental bottom perspective view of FIG. 2 ; FIG. 5 is an environmental side perspective view of FIG. 2 ; FIG. 6 is an environmental bottom elevational view of FIG. 2 ; and, FIG. 7 is an environmental side elevational of FIG. 2 . In the drawings, the broken lines depict unclaimed subject matter and form no part of the claimed design.

同族专利

暂无同族专利