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Donahoe has published over 230 peer-reviewed publications in developmental biology, concentrating on Mullerian Inhibiting Substance as a potential anticancer agent against human ovarian carcinomas, as well as the genetics of sex differentiation and a number of other congenital anomalies for which she has been steadily funded by the NIH. She and her colleagues, particularly David MacLaughlin, hold a number of patents on MIS. They purified the human MIS, cloned the MIS gene and that of its receptors, studied their regulation and their roles in the growth, diagnosis, and treatment of ovarian and other reproductive tumors, and used MIS as a marker in the diagnosis of human tumors in human intersex disorders.
Donahoe is a member of the National Academy of Sciences, Institute of Medicine of the National Academy of Sciences, and American Academy of Arts and Sciences. She served as President of the Boston Surgical Society and is President-elect of the American Pediatric Surgical Association. She has received many research prizes and honorary degrees for her work on MIS but her fondest dream is to see it developed as a therapeutic for ovarian and other reproductive cancers.
Donahoe is a member of the National Academy of Sciences, Institute of Medicine of the National Academy of Sciences, and American Academy of Arts and Sciences. She served as President of the Boston Surgical Society and is President-elect of the American Pediatric Surgical Association. She has received many research prizes and honorary degrees for her work on MIS but her fondest dream is to see it developed as a therapeutic for ovarian and other reproductive cancers.
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James A Howard, Lucija Hok,Richard L Cate, Nathaniel J Sanford,Kaitlin N Hart, Edmund Ae Leach, Alena S Bruening,David Pépin,Patricia K Donahoe,Thomas B Thompson
bioRxiv : the preprint server for biology (2024)
Lindsey M. Vansandt,Marie-Charlotte Meinsohn,Philippe Godin,Nicholas Nagykery,Natalie Sicher,Motohiro Kano,Aki Kashiwagi,Maeva Chauvin,Hatice D. Saatcioglu, Julie L. Barnes, Amy G. Miller, Amy K. Thompson,
M Chauvin,M-C Meinsohn, S Dasari, P May, S Iyer,N M P Nguyen,E Oliva, Z Lucchini, N Nagykery, A Kashiwagi, R Mishra, R Maser,
Cell reportsno. 7 (2023): 112730-112730
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JOURNAL OF PEDIATRIC GENETICSno. 1 (2023): 29-34
American journal of human geneticsno. 10 (2023): 1787-1803
Sarah Bick, Jennifer Lyu,Tabitha Poorvu,Patricia Donahoe,Jill Zalieckas,Kathryn Gray, David Zurakowski,Frances High,Terry Buchmiller
Genetics in Medicine Openno. 1 (2023): 100655-100655
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Yi Li,Lina Wei,Marie-Charlotte Meinsohn,Rana Suliman,Maeva Chauvin, Jim Berstler, Kate Hartland, Mark M Jensen,Natalie A Sicher,Nicholas Nagykery,Patricia K Donahoe,David Pepin
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