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个人简介
My expertise is in the field of respiratory viruses, in particular influenza viruses. My studies aim to understand the molecular and cellular basis of the pathogenesis, host range restrictions and transmissibility of influenza viruses. The approach includes the generation of recombinant viruses with defined mutations. This strategy has contributed to the production of novel influenza pandemic vaccines. In principle, the work employs the most appropriate virus strains and relevant cell or animal models. Primary influenza clinical strains are obtained through a long-standing collaboration with the Health Protection Agency, and viruses are studied on primary human airway cells and in ferrets. Translational aspects include analysing mode of action and resistance mechanisms of antiviral compounds, and characterization of novel cell substrates and attenuated virus backbones for influenza vaccines. The laboratory is funded by MRC, BBSRC, the Wellcome Trust and commercial bodies.
研究兴趣
论文共 304 篇作者统计合作学者相似作者
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Maximillian N. J. Woodall, Ana-Maria Cujba,Kaylee B. Worlock, Katie-Marie Case,Tereza Masonou, Masahiro Yoshida,Krzysztof Polanski,Ni Huang, Rik G. H. Lindeboom,Lira Mamanova, Liam Bolt, Laura Richardson,
Jiahui Zou,Meijun Jiang,Rong Xiao, Huimin Sun, Hailong Liu,Thomas Peacock,Shaoyu Tu, Tong Chen,Jinli Guo,Yaxin Zhao,Wendy Barclay,Shengsong Xie,
biorxiv(2024)
Patricia P. Ogger, Minerva Garcia Martín, Soyeon Jang,Jie Zhou,Jonathan Brown,Ksenia Sukhova,Wilhelm Furnon,Arvind H. Patel,Vanessa Cowton,Massimo Palmarini,Wendy S. Barclay,Cecilia Johansson
Lorenzo Subissi,James Richard Otieno, Nathalie Worp,Homa Attar Cohen,Bas B Oude Munnink, Laith J Abu-Raddad,Erik Alm, Amal Barakat,Wendy S Barclay, Jinal N Bhiman, Leon Caly,Meera Chand,
Nature medicinepp.1-4, (2024)
Patricia P. Ogger, Minerva Garcia Martín, Soyeon Jang,Jie Zhou,Jonathan Brown,Ksenia Sukhova,Wilhelm Furnon,Arvind H. Patel,Vanessa Cowton,Massimo Palmarini,Wendy S. Barclay,Cecilia Johansson
Oluwadamilola D Ogunjinmi, Tukur Abdullahi, Riaz-Ali Somji,Charlotte L Bevan,Wendy S Barclay,Nigel Temperton,Greg N Brooke,Efstathios S Giotis
Journal of medical virologyno. 3 (2024): e29540-e29540
MICROBIOLOGY SPECTRUMno. 4 (2024): e0363423-e0363423
biorxiv(2023)
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