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Much of our current research interests are in identifying key functional groups of bacteria within the intestinal microbiota of humans and animals. Although intestinal microbiotas are extremely complex entities, with many species sharing overlapping functional capabilities, it is thought that some deleterious or beneficial activities are limited to a relatively small range of species. In particular, we are interested in microbial contributors to the development of chronic ailments. For example, we are interested in bacterial consumers of lactate, accumulation of which has been linked to chronic diseases such as inflammatory bowel disease, and producers of trimethylamine (TMA), which has been linked to cardiovascular disease. We are also interested the role that host diet plays in the prevalence and activities of these key functional gut bacterial groups.
In addition, we study the role that the intestinal microbiota plays in inhibiting pathogenic microbes. We use the Rowett Institute's extensive collection of gut bacteria to screen for individual strains that show activity against a range of important pathogens of humans and animals. We are also members of the EU-funded FunHoMic network, as part of which we are particularly interested in identifying specific microbes, and mechanisms, involved in antagonistic activity against the fungal pathogen Candida albicans in the colon.
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Benjamin Momo Kadia,Anouschka S. Ramsteijn,Teena Dasi, Umi Fahmida,Bharati Kulkarni,Babacar Faye, Min Kyaw Htet, Doudou Sow,Rajender Rao Kalashikam, Ritu Sharma, Arienta R. P. Sudibya, Sari Kusuma,
Benjamin Momo Kadia, Marietou Khouma, Doudou Sow,Babacar Faye,Anouschka S. Ramsteijn,Beatriz Calvo-Urbano, Modou L. Jobarteh,Elaine Ferguson,Paul Haggarty,Joanne P. Webster,Alan W. Walker,Claire Heffernan,
Biomedicinesno. 5 (2023): 1338-1338
Nature microbiologyno. 8 (2023): 1392-1396
Frontiers in nutrition (2023): 1139880
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Umer Zeeshan Ijaz,Ozan Gundogdu,Ciara Keating,Miriam van Eekert,Walter Gibson,Julian Parkhill,Faraji Abilahi, Benard Liseki,Viet-Anh Nguyen, Steven Sudgen,Christopher Quince,Jeroen H. J. Ensink,
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