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个人简介
The Kostic lab strives to uncover and understand the immunomodulatory functions of the symbiotic microbiota and their impact on type 1 diabetes and related autoimmune diseases. Lab members are involved in one or more of the following 3 research themes:
(1) Computational analysis of large patient cohorts including genomic, transcriptomic, and metabolomic datasets of the host and gut microbiome to identify microbial products associated with disease or health.
(2) Engineering microbes via synthetic biology to enhance or disrupt these products.
(3) Mechanistic studies in humanized, gnotobiotic mouse models to understand how these microbial products impact disease.
(1) Computational analysis of large patient cohorts including genomic, transcriptomic, and metabolomic datasets of the host and gut microbiome to identify microbial products associated with disease or health.
(2) Engineering microbes via synthetic biology to enhance or disrupt these products.
(3) Mechanistic studies in humanized, gnotobiotic mouse models to understand how these microbial products impact disease.
研究兴趣
论文共 96 篇作者统计合作学者相似作者
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Research square (2023)
MSystemsno. 2 (2023)
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Zohorul Islam, Selma Zimmerman,Jon A. Weidanz, José Ordovás-Montañés,Michael Robben,Jacob M. Luber,Aleksandar D. Kostic
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Marsha Christanvia Wibowo,Zhen Yang,Theodore A Chavkin, Brian Nguyen,Loc-Duyen Pham, Tian Lian Huang,Matthew D Lynes,Yu-Hua Tseng,Aleksandar D Kostic
biorxiv(2022)
Braden T Tierney,Yingxuan Tan,Zhen Yang,Bing Shui, Michaela J Walker, Benjamin M Kent,Aleksandar D Kostic,Chirag J Patel
Tao Xu,Lidan Zhao,Md Zohorul Islam, Loc Duyen Pham, Martina Sassone Corsi, Ramnik J. Xavier,Christophe Benoist,Aleksandar David Kostic
Social Science Research Network (2022)
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