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We have established a scaleable and clinically compatible system for generating and propagating neural stem cells from human embryonic stem (ES) cells. Using this platform, and building on our work on mouse ES cells demonstrating a correlation of developmental restriction with the onset of gliogenesis, we are investigating the interplay between extrinsic signals and intrinsic determinants on developmental plasticity in a human context.
We have established a scaleable and clinically compatible system for generating and propagating neural stem cells from human embryonic stem (ES) cells. Using this platform, and building on our work on mouse ES cells demonstrating a correlation of developmental restriction with the onset of gliogenesis, we are investigating the interplay between extrinsic signals and intrinsic determinants on developmental plasticity in a human context.
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crossref(2024)
Stefan Yordanov, Shuaib Khan, Danial Stubbs,Benjamin Davies,Thomas Santarius,Peter Hutchinson,Alexis Joannides
Social Science Research Networkno. 5 (2023): e271-e278
Acta neurochirurgicano. 10 (2023): 2903-2911
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Brain and Spine (2023): 101916-101916
Rohitashwa Sinha, Riccardo Masina, Cristina Morales, Katherine Burton,Yizhou Wan,Alexis Joannides,Richard J Mair,Robert C Morris,Thomas Santarius,Tom Manly,Stephen J Price
Saniya Mediratta,Stefan Yordanov,Jibin Francis, G. Balamurali,Karol Budohoski,Alexis Joannides,Tariq Khan, Radek Kindl,Michael Martin, Colum Nolan, benezer Tirsit, Sarah Woodrow,
Brain and spine (2023): 101943-101943
NIHR open research (2023): 34-34
Serena Cole, Pan Liu, Kimi Owashi, Benjamin Dias Dougan,Tomasz Matys,Peter Smielewski,Olivier Baledent,Alexis Joannides
Brain and Spine (2023): 102294-102294
Brain and Spine (2023): 102295-102295
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