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Research Overview
Research interests include projects looking at: 1) determing how select expression of cell surface co-inhibitory proteins (check-point proteins) and their ligands, on innate immune cells as well as non-immune cells; alter the morbid events associated with adult sepsis. 2) Utilizing a novel model of indirect-acute lung (iALI) to ask how check-point protein expression affects the patho-mechanisms driving iALI. Finally, 3) since the neonate possesses a unique/ naive immune system and is more susceptible to morbid response in the face of infectious challenge, we are examining if the expression of check-point protein family members have a comparative impact on the neonate's response to septic insult.
Research interests include projects looking at: 1) determing how select expression of cell surface co-inhibitory proteins (check-point proteins) and their ligands, on innate immune cells as well as non-immune cells; alter the morbid events associated with adult sepsis. 2) Utilizing a novel model of indirect-acute lung (iALI) to ask how check-point protein expression affects the patho-mechanisms driving iALI. Finally, 3) since the neonate possesses a unique/ naive immune system and is more susceptible to morbid response in the face of infectious challenge, we are examining if the expression of check-point protein family members have a comparative impact on the neonate's response to septic insult.
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Frontiers in Immunology (2024)
Inflammation Researchno. 1 (2023): 1-4
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SHOCKno. 3 (2023): 443-449
Brandon E. Armstead,Brandon E. Armstead,Brandon E. Armstead, Chung Sunny Lee, Chung Sunny Lee,Yaping Chen,Yaping Chen,Runping Zhao,Runping Zhao,Chun-Shiang Chung,Chun-Shiang Chung,Alger M. Fredericks,
Frontiers in Medicine (2023): 1003121-1003121
Inflammation Researchno. 1 (2023): 1-4
Journal of leukocyte biology (2023)
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