Alfred Sommer
Professor Emeritus
Department of Epidemiology
Bloomberg School of Public Health, Johns Hopkins University;Department of International Health, Bloomberg School of Public Health, Johns Hopkins University;School of Medicine, Johns Hopkins University;Center for Global Health, Johns Hopkins University
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His long-term, continuing research involves the cause, magnitude, consequences, and control of vitamin A deficiency and, most recently, those of related micronutrients. In a series of complex intervention trials Sommer conducted in Indonesia (1976-1980), he and his research team discovered that vitamin A deficiency was far more common than previously recognized, and that even mild vitamin A deficiency dramatically increases childhood mortality rates, primarily because this deficiency reduces resistance to infectious diseases such as measles and diarrhea. Parallel studies Sommer organized with colleagues in Africa demonstrated that most cases of measles-associated pediatric blindness were also related to low vitamin A levels.
To prove these observations definitively, Sommer and his colleagues ran a number of large-scale, community-based, randomized trials from 1983 through 1992 and demonstrated the link between even mild vitamin A deficiency and pediatric mortality.
To prove these observations definitively, Sommer and his colleagues ran a number of large-scale, community-based, randomized trials from 1983 through 1992 and demonstrated the link between even mild vitamin A deficiency and pediatric mortality.
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American Journal of Ophthalmology (2023)
JAMA OPHTHALMOLOGYno. 1 (2022): 55-55
OPHTHALMOLOGYno. 1 (2021): 28-29
Principles and Practice of Clinical Trialspp.1-16, (2020)
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