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Our goal is to describe the biochemical mechanism of the Ubiquitin Proteasome System in a physiologically relevant context. A deeper understanding of the UPS leads to the discovery of unexpected ways through which cellular processes are regulated. Lab members translate the insights we gain into the mechanism into strategies to interfere in the UPS experimentally and eventually therapeutically. As experimental methods, we use techniques including protein engineering, quantitative biochemical assays, cell biology, genome-scale screens, and single molecule biophysics.
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论文共 113 篇作者统计合作学者相似作者
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Adam J Anthony, Amit K S Gautam,Lohra M Miller, Yiran Ma, Anya G Hardwick, Anu Sharma,Subhadip Ghatak,Andreas Matouschek,Martin F Jarrold,David E Clemmer
Analytical chemistryno. 5 (2024): 2273-2273
ANALYTICAL CHEMISTRYno. 5 (2024): 2273-2273
The journal of physical chemistry lettersno. 21 (2023): 5014-5017
Caroline Davis, B L Spaller, Erin Choi, Joseph Kurrasch, Haemin Chong,Suzanne Elsasser,Daniel Finley,Andreas Matouschek
bioRxiv : the preprint server for biology (2023)
Adam J Anthony,Amit K S Gautam,Lohra M Miller, Yiran Ma, Anya G Hardwick, Anu Sharma,Subhadip Ghatak,Andreas Matouschek,Martin F Jarrold,David E Clemmer
Ramhari Kumbhar,Anthony Sanchez, Jullian Perren,Fade Gong,David Corujo,Frank Medina, Sravan K Devanathan,Blerta Xhemalce,Andreas Matouschek,Marcus Buschbeck,Bethany A Buck-Koehntop,Kyle M Miller
biorxiv(2021)
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