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Research description
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes (writers) responsible. I have a keen interest in identifying protein domains that specifically bind (readers) to modified histones. This information has been used to enable the development of small molecule inhibitors (to both writers and readers).
More recently, my focus has switched to the analysis of post-transcriptional RNA modifications and the relevant enzymes. Ultimately, I hope to be able to use the knowledge gained to develop novel anti-cancer therapeutic compounds.
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes (writers) responsible. I have a keen interest in identifying protein domains that specifically bind (readers) to modified histones. This information has been used to enable the development of small molecule inhibitors (to both writers and readers).
More recently, my focus has switched to the analysis of post-transcriptional RNA modifications and the relevant enzymes. Ultimately, I hope to be able to use the knowledge gained to develop novel anti-cancer therapeutic compounds.
Research Interests
Papers共 127 篇Author StatisticsCo-AuthorSimilar Experts
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Sarah Picaud,Oleg Fedorov,Angeliki Thanasopoulou,Katharina Leonards,Katherine Jones,Julia Meier,Heidi Olzscha,Octovia Monteiro,Sarah Martin,Martin Philpott,Anthony Tumber,Panagis Filippakopoulos,Clarence Yapp,Christopher Wells,Ka Hing Che,Andrew Bannister,Samuel Robson,Umesh Kumar,Nigel Parr,Kevin Lee,Dave Lugo,Philip Jeffrey,Simon Taylor,Matteo L. Vecellio,Chas Bountra,Paul E. Brennan,Alison O'Mahony,Sharlene Velichko,Susanne Müller,Duncan Hay,Danette L. Daniels,Marjeta Urh,Nicholas B. La Thangue,Tony Kouzarides,Rab Prinjha,Jürg Schwaller,Stefan Knapp
crossref(2023)
Sarah Picaud,Oleg Fedorov,Angeliki Thanasopoulou,Katharina Leonards,Katherine Jones,Julia Meier,Heidi Olzscha,Octovia Monteiro,Sarah Martin,Martin Philpott,Anthony Tumber,Panagis Filippakopoulos,Clarence Yapp,Christopher Wells,Ka Hing Che,Andrew Bannister,Samuel Robson,Umesh Kumar,Nigel Parr,Kevin Lee,Dave Lugo,Philip Jeffrey,Simon Taylor,Matteo L. Vecellio, Chas Bountra,Paul E. Brennan,Alison O'Mahony,Sharlene Velichko,Susanne Müller,Duncan Hay,Danette L. Daniels, Marjeta Urh,Nicholas B. La Thangue,Tony Kouzarides,Rab Prinjha,Jürg Schwaller,Stefan Knapp
crossref(2023)
NUCLEIC ACIDS RESEARCHno. 15 (2023): 7709-7713
Sarah Picaud,Oleg Fedorov,Angeliki Thanasopoulou,Katharina Leonards,Katherine Jones,Julia Meier,Heidi Olzscha,Octovia Monteiro,Sarah Martin,Martin Philpott,Anthony Tumber,Panagis Filippakopoulos,Clarence Yapp,Christopher Wells,Ka Hing Che,Andrew Bannister,Samuel Robson,Umesh Kumar,Nigel Parr,Kevin Lee,Dave Lugo,Philip Jeffrey,Simon Taylor,Matteo L. Vecellio,Chas Bountra,Paul E. Brennan,Alison O'Mahony,Sharlene Velichko,Susanne Müller,Duncan Hay,Danette L. Daniels,Marjeta Urh,Nicholas B. La Thangue,Tony Kouzarides,Rab Prinjha,Jürg Schwaller,Stefan Knapp
crossref(2023)
Eliza Yankova,Wesley Blackaby,Mark Albertella,Justyna Rak,Etienne De Braekeleer,Georgia Tsagkogeorga,Ewa S. Pilka,Demetrios Aspris,Dan Leggate,Alan G. Hendrick,Natalie A. Webster,Byron Andrews,Richard Fosbeary, Patrick Guest,Nerea Irigoyen,Maria Eleftheriou,Malgorzata Gozdecka,Joao M. L. Dias,Andrew J. Bannister,Binje Vick,Irmela Jeremias,George S. Vassiliou,Oliver Rausch,Konstantinos Tzelepis,Tony Kouzarides
Natureno. 7860 (2021): 597-601
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Author Statistics
#Papers: 127
#Citation: 34760
H-Index: 60
G-Index: 97
Sociability: 6
Diversity: 3
Activity: 25
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