Current areas of interest Physiopathology and therapy of atherosclerosis: Oxidation of LDL and atherosclerosis Factors determining the resistance of LDL to oxidation Risk factors for atherosclerosis and resistance of LDL to oxidation Oxidized LDL and free radical generation in endothelial cells Relationships among oxidative stress, endothelial dysfunction and subclinical atherosclerosis Relationships among oxidative stress, endothelial dysfunction and hypertension- Effect of antioxidant therapy on oxidative stress in vivo- Relationship between generation of free radicals in endothelial cells and nitric oxide availability- Evaluation of oxidative stress in vivo- Mechanisms of expansion of necrotic core in atherosclerotic plaques