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Dr. Orr and her team investigate glial-neuronal communication and mitochondrial signaling in normal brain function and pathophysiological processes associated with dementia and other disorders. Her research focuses on three types of interrelated molecular signaling mechanisms: neuroimmune, oxidative, and G protein-coupled. Using diverse approaches, the team investigates mechanisms of astrocytic signaling and astrocytic effects on neuronal functions and disease-related processes, including neuroinflammation, proteinopathy, synaptic alterations, and behavioral functions. In addition, the team has parallel efforts devoted to therapeutic discovery and translating their findings into promising new treatments for dementia.
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论文共 25 篇作者统计合作学者相似作者
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Trends in Neurosciencesno. 4 (2024): 289-302
Daniel Barnett,Kirsten Bohmbach, Valentin Grelot,Alexandre Charlet,Glenn Dallerac, Yeon Ha Ju,Jun Nagai,Anna G. Orr
JOURNAL OF NEUROSCIENCEno. 45 (2023): 7463-7471
International Review of Neurobiology (2023): 121-154
International review of neurobiology (2023): 121-154
biorxiv(2022)
Avital Licht Murava, Samantha Meadows,Fernando Palaguachi,Soomin C Song,Yaron Bram, Constance Zhou,Robert E Schwartz,Robert C Froemke,Adam L Orr,Anna G Orr
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