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Dr. Grace's research interests lie at the interface of neurobiology and psychiatry. Experiments conducted in his laboratory combine in vivo and in vitro electrophysiological recordings of identified neurons with behavioral and neuroanatomical techniques to study central dopaminergic systems, with the ultimate goal of determining the neurobiological correlates of mental disorders and the modes of action of psychotherapeutic drugs. Ongoing studies into the neurobiology of schizophrenia involve study of the interaction of the prefrontal cortex and antipsychotic drugs with subcortical dopamine systems, and examining the impact of developmental disruption on limbic system function, as a model for the pathophysiological changes underlying schizophrenia in humans. The mechanism of deep brain stimulation in treatment of obsessive compulsive disorder and the impact of stress on drug abuse are also investigated in anesthetized and awake animals.
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Nicholas R Livingston,Amanda Kiemes,Gabriel A Devenyi,Samuel Knight,Paulina B Lukow,Luke A Jelen,Thomas Reilly, Aikaterini Dima,Maria Antonietta Nettis,Cecilia Casetta, Tyler Agyekum,Fernando Zelaya,
Schizophrenia bulletin (2024)
Michaela Krivosova, Licia Vellucci, Daniele Cavaleri, Luís Afonso Fernandes, Edison Leung,Gabriella Gobbi,Anthony A. Grace,Kazutaka Ikeda, María A. Oquendo,Eric Vermetten,Joseph Zohar,Asilay Şeker
International Journal of Psychiatric Trainees (2023)
SCHIZOPHRENIA RESEARCH (2023): 32-39
medRxiv : the preprint server for health sciences (2023)
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NEUROPSYCHOPHARMACOLOGY (2023): 167-168
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CURRENT OPINION IN PSYCHIATRYno. 3 (2023): 172-178
Authorea (Authorea) (2023)
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