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职业迁徙
个人简介
Areas of Specialization:
1. Gold Biochemistry (Anti-arthritic Drugs)
The main research area emphasize the biological and inorganic chemistry of gold(I)-thiolate complexes which are active as antiarthritic agents. The ligand exchange reactions are being investigated by using NMR spectroscopy.
2. Thione/Thionine/Selenomethionine Complexes
Imidazolidine-2 thione/Methionine/Selenomethionie and their derivatives are used as model ligands to synthesize various heavy metal complexes.
3. Captopril (A High Blood Pressure Drug)
Captopril which has been used as a high blood pressure drug forms a crystalline complex with gold(I), which is first time in the history of gold(I)-thiolate complex is being crystalline. NMR is used to study the interaction of captopril with other heavy metal ions.
4. Impact of Cyanide ion on Smokers who are treated with Gold Drugs
We are currently studying the reaction mechanism of cyanide ion with gold(I) drugs. Smokers on gold(I) therapy is found to have more toxic effects than nonsmokers. NMR is used to study the exchange reactions.
5. Red Blood Cells/ Serum Albumin
The interaction of heavy metal ions with red blood cells as well as with serum albumin being investigated by NMR spectroscopy.
6. R3PAu13C15N and R3PAuS13C15N complexes
Labeled R3PAuCN and R3PAuSCN new complexes are being synthesized which may have biological impact.
7. Selenocyanate and thiocyanate interactions
Recently my Ph.D. student is working on the interaction of Selenocyanate and thiocyanate with Gold (I) drugs to understand the disproportionation reaction of the type CNSe-Au-thiols.
8. Solid state NMR studies Cd(II)-thione/selone complexes
We have recently started synthesizing various Imidazolidine-2-thione and its derivatives complexes with Cd(II) and study them solution as well as in solid state in collaboration with Dr. M. I. M. Wazeer.
9. Ag13C15N complexes with thiones/selones
Labeled Ag13C15N complexes are being synthesized with thiones/selones and study them with 109Ag NMR spectroscopy
10. Novel Anticancer Gold (III) Complexes
Recently we are involved in the collaboration with SAAD specialist hospital and Dammam Univ. Hospital to develop new gold (III) anti cancer drug. My students are involved in the synthesis, characterizations and anti-cancer measurement activities of several gold(III) and gold(I) complexes.
1.11Collaboration with the Physics Dept. on measurement of the elements
1. Gold Biochemistry (Anti-arthritic Drugs)
The main research area emphasize the biological and inorganic chemistry of gold(I)-thiolate complexes which are active as antiarthritic agents. The ligand exchange reactions are being investigated by using NMR spectroscopy.
2. Thione/Thionine/Selenomethionine Complexes
Imidazolidine-2 thione/Methionine/Selenomethionie and their derivatives are used as model ligands to synthesize various heavy metal complexes.
3. Captopril (A High Blood Pressure Drug)
Captopril which has been used as a high blood pressure drug forms a crystalline complex with gold(I), which is first time in the history of gold(I)-thiolate complex is being crystalline. NMR is used to study the interaction of captopril with other heavy metal ions.
4. Impact of Cyanide ion on Smokers who are treated with Gold Drugs
We are currently studying the reaction mechanism of cyanide ion with gold(I) drugs. Smokers on gold(I) therapy is found to have more toxic effects than nonsmokers. NMR is used to study the exchange reactions.
5. Red Blood Cells/ Serum Albumin
The interaction of heavy metal ions with red blood cells as well as with serum albumin being investigated by NMR spectroscopy.
6. R3PAu13C15N and R3PAuS13C15N complexes
Labeled R3PAuCN and R3PAuSCN new complexes are being synthesized which may have biological impact.
7. Selenocyanate and thiocyanate interactions
Recently my Ph.D. student is working on the interaction of Selenocyanate and thiocyanate with Gold (I) drugs to understand the disproportionation reaction of the type CNSe-Au-thiols.
8. Solid state NMR studies Cd(II)-thione/selone complexes
We have recently started synthesizing various Imidazolidine-2-thione and its derivatives complexes with Cd(II) and study them solution as well as in solid state in collaboration with Dr. M. I. M. Wazeer.
9. Ag13C15N complexes with thiones/selones
Labeled Ag13C15N complexes are being synthesized with thiones/selones and study them with 109Ag NMR spectroscopy
10. Novel Anticancer Gold (III) Complexes
Recently we are involved in the collaboration with SAAD specialist hospital and Dammam Univ. Hospital to develop new gold (III) anti cancer drug. My students are involved in the synthesis, characterizations and anti-cancer measurement activities of several gold(III) and gold(I) complexes.
1.11Collaboration with the Physics Dept. on measurement of the elements
研究兴趣
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Journal of Molecular Structure (2024): 136914-136914
JOURNAL OF MOLECULAR STRUCTURE (2024)
DALTON TRANSACTIONSno. 3 (2024): 1099-1104
Anti-cancer agents in medicinal chemistryno. 5 (2024): 379-388
INORGANICA CHIMICA ACTA (2024): 121922
Ambarish Mondal, Subhadarshinee Behera,Hemanta K. Kisan,Anvarhusein A. Isab,Swapan K. Chandra, Jasmine Sultana,Saptak Banerjee,Joydev Dinda
INORGANICA CHIMICA ACTA (2024): 121796-121796
NEW JOURNAL OF CHEMISTRYno. 1 (2023): 284-296
Prafulla Kumar Behera,Lakshmikanta Maity,Sraddhya Roy,Ananya Das, Priyanka Sahu,Hemanta K. Kisan,Avtar Changotra,Anvarhusein A. Isab,Mohammed Fettouhi, Aparajita Bairagi,Nabanita Chatterjee,Joydev Dinda
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