基本信息
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职业迁徙
个人简介
My research projects mainly focus on the identification and investigation of the functions of tumor suppressor genes in cancers, especially in the nasopharyngeal carcinoma (NPC), which is endemic in the Southeast Asia and Southeast China. I am also interested in studying the role of a oncovirus, Epstein-Barr Virus (EBV), in the development of NPC. I am studying the roles of EBV in regulating the epigenetic changes in the host genome and its contribution to the NPC tumorigenesis.
Research Grant record
2009 Small Project Funding, The University of Hong Kong
Title: Functional investigation of candidate tumor suppressor gene,
Protein tyrosine phosphatase receptor type G functional domains
and angiogenesis effect.
Funding amount: HKD $66,6674
2012 Small Project Funding, The University of Hong Kong
Title: Investigation of the role of Epstein-Barr Virus in epigenetic
regulation in nasopharyngeal carcinoma
Funding amount: HKD $80,000
University of Hong Kong/China Medical Board Grants for
overseas training in the University of Birmingham, UK
2013 Seed Funding, The University of Hong Kong
Title: Investigation of EBV-associated host cell histone
modification and gene expression changes in nasopharyngeal
carcinoma by next-generation sequencing
Funding amount: HKD $120,000
2015 General Research Fund (GRF), Research Grants Council, HKSAR.
Title: Functional and mechanistic characterizations of a candidate
tumor suppressor gene, Mirror Image Polydactyly 1, in
Nasopharyngeal Carcinoma
Funding amount: HKD $961,461
Small Project Funding, The University of Hong Kong.
Title: Functional validation of a novel DUB3 somatic mutation in
tumors of nasopharyngeal carcinoma
Funding amount: HKD $80,000
2016 General Research Fund (GRF), Research Grants Council, HKSAR.
Elucidation of the role of Epstein-Barr Virus in modulating DNA
damage repair and cancer-associating signaling pathways via
bivalent H3K4me3 and H3K27me3 histone modifications in
nasopharyngeal epithelial and cancer cell.
Funding amount: HKD $1,054,087
Research Grant record
2009 Small Project Funding, The University of Hong Kong
Title: Functional investigation of candidate tumor suppressor gene,
Protein tyrosine phosphatase receptor type G functional domains
and angiogenesis effect.
Funding amount: HKD $66,6674
2012 Small Project Funding, The University of Hong Kong
Title: Investigation of the role of Epstein-Barr Virus in epigenetic
regulation in nasopharyngeal carcinoma
Funding amount: HKD $80,000
University of Hong Kong/China Medical Board Grants for
overseas training in the University of Birmingham, UK
2013 Seed Funding, The University of Hong Kong
Title: Investigation of EBV-associated host cell histone
modification and gene expression changes in nasopharyngeal
carcinoma by next-generation sequencing
Funding amount: HKD $120,000
2015 General Research Fund (GRF), Research Grants Council, HKSAR.
Title: Functional and mechanistic characterizations of a candidate
tumor suppressor gene, Mirror Image Polydactyly 1, in
Nasopharyngeal Carcinoma
Funding amount: HKD $961,461
Small Project Funding, The University of Hong Kong.
Title: Functional validation of a novel DUB3 somatic mutation in
tumors of nasopharyngeal carcinoma
Funding amount: HKD $80,000
2016 General Research Fund (GRF), Research Grants Council, HKSAR.
Elucidation of the role of Epstein-Barr Virus in modulating DNA
damage repair and cancer-associating signaling pathways via
bivalent H3K4me3 and H3K27me3 histone modifications in
nasopharyngeal epithelial and cancer cell.
Funding amount: HKD $1,054,087
研究兴趣
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