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His work on computing with neural circuits is centered on Neural Computing Engines and on NeuroInformation Processing Machines. He pioneered formal theoretical methods of neural encoding and decoding (Time Encoding Machines) and functional identification of dendritic stimulus processors and biophysical spike generators (Channel Identification Machines). His research group created and implemented Spike Processing Machines and Phase Processing Machines in the analog domain (graded potentials) and in the spike domain on clusters of GPUs. Some of the code developed by his collaborators is available for free download. His in vivo work on Reverse Engineering the Fruit Fly Brain primarily addresses sensory processing in the early olfactory system of the Drosophila.
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Orie T Shafer,Gabrielle J Gutierrez, Kimberly Li, Amber Mildenhall, Daphna Spira, Jonathan Marty,Aurel A Lazar,Maria de la Paz Fernandez
bioRxiv (Cold Spring Harbor Laboratory) (2021)
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