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Bert Vogelstein, M.D., was the first scientist to elucidate the molecular basis of a common human cancer. In particular, he and his colleagues have demonstrated that colorectal tumors result from the gradual accumulation of genetic alterations in specific oncogenes and tumor suppressor genes. His group’s discovery and analysis of these genes and their functions represent a landmark in the application of molecular biology to the study of human disease. His work on colorectal cancers forms the paradigm for much of modern cancer research, with profound implications for diagnostic and therapeutic strategies in the future.
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Adam H. Buchanan,Anne Marie Lennon, Seema P. Rego, Omair A. Choudhry, Paul Z. Elias, Jennifer R. Sadler,Joshua D. Cohen, Christopher B. Douville, Ashley M. Honushefsky,Alison Klein, Zachary M. Salvati,Kathleen Sheridan,
JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): 3037-3037
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Journal of computer assisted tomographyno. 6 (2023): 845-849
Brian J. Mog,Sarah R. DiNapoli,Michael S. Hwang, Tushar D. Nichakawade,Jacqueline Douglass,Emily Han‐Chung Hsiue,Katharine M. Wright,Alexander H. Pearlman,Maximilian F. Konig,Suman Paul,Nicolas Wyhs, Nikita Marcou,
Cancer Researchno. 8_Supplement (2023): LB095-LB095
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N. Papadopoulos,A.M. Lennon, P. Elias, S. Rego, O. Choudhry, D. Flake,J. Cohen,C. Douville, A. Honushefsky, I. Kinde,A. Klein, Z. Salvati,
Annals of Oncology (2023): S262-S263
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Natureno. 7977 (2023): E28-E29
Cell Reports Medicineno. 8 (2023): 101148-101148
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