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I have a long term interest in the immune response to persistent viral infections. Presently we are studying the pathogenesis of gastrointestinal viruses using murine norovirus as a model virus. This can establish both acute and persistent infections. It may also spread from the gut to cause a systemic infection that can lead to pathology in different organ systems. As such it is both a good model system for studying gastrointestinal immunity and mechanisms of viral persistence. We are investigating the role of different cell types and factors in the gut that protect from infection as well as properties of the virus itself that affect its pathogenesis.
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Journal of veterinary internal medicine (2024)
Ernest T Aguinam,Angalee Nadesalingam,Andrew Chan,Peter Smith,Minna Paloniemi,Diego Cantoni, Jessica Gronlund, Helen Gronlund,George W Carnell,Javier Castillo-Olivares,Nigel Temperton,Barbara Blacklaws,
The journal of allergy and clinical immunology. Globalno. 2 (2023): 100091-100091
medRxiv (Cold Spring Harbor Laboratory) (2022)
MicrobiologyOpenno. 4 (2021): e1215-e1215
JOURNAL OF VETERINARY INTERNAL MEDICINEno. 2.0 (2020): 542.0-543.0
Samuel C. B. Stubbs,Barbara A. Blacklaws,Benediktus Yohan, Frilasita A. Yudhaputri, Rahma F. Hayati,Brian Schwem,Edsel M. Salvaña,Raul V. Destura,James S. Lester,Khin S. Myint,R. Tedjo Sasmono,Simon D. W. Frost
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