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个人简介
Dr. Barlogie’s scientific career has focused on biological and therapeutic research, including chemotherapy, immunotherapy, and hematopoietic stem cell transplantation. He developed the first effective salvage regimen (VAD) for melphalan-prednisone refractory myeloma, introduced autologous transplantation for myeloma, and identified thalidomide as a first-in-class novel agent for the treatment of myeloma. Together with John Shaughnessy, PhD, who also recently joined the Mount Sinai Health System, Dr. Barlogie developed gene expression profiling to identify molecular subclasses of myeloma and established a highly predictive risk model.
Under his leadership, multiple myeloma has become a curable disease when applying his Total Therapy approach – meaning using all active agents upfront, followed by tandem melphalan-based autotransplants, consolidation chemotherapy and maintenance. He is now focusing his attention on the 15% of patients presenting with genomically defined high-risk MM, by applying metronomically scheduled chemotherapy and targeting mutations.
Under his leadership, multiple myeloma has become a curable disease when applying his Total Therapy approach – meaning using all active agents upfront, followed by tandem melphalan-based autotransplants, consolidation chemotherapy and maintenance. He is now focusing his attention on the 15% of patients presenting with genomically defined high-risk MM, by applying metronomically scheduled chemotherapy and targeting mutations.
研究兴趣
论文共 920 篇作者统计合作学者相似作者
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CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S25-S26
Blood advancesno. 3 (2023): 703-707
Blood (2023): 882
Blood (2023): 1066
Frits van Rhee,Susann M. Szmania, Myles Dillon, Anne M. van Abbema,Xin Li, Mary K. Stone,Tarun K. Garg,JuMei Shi, Amberly M. Moreno-Bost,Rui Yun,Balaji Balasa,Bishwa Ganguly,
crossref(2023)
Journal of hematology & oncologyno. 1 (2023): 70-5
Blood (2023): 3594
JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): e20053-e20053
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JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): 8059-8059
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