Ben Z. Stanger
教授
Division of Gastroenterology
Department of Medicine, Perelman School of Medicine, University of Pennsylvania;Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania;Penn Pancreatic Cancer Research Center, Perelman School of Medicine, University of Pennsylvania
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个人简介
Pancreatic Ductal Adenocarcinoma (PDAC) is poised to become the second leading cause of cancer death in the United States. This poor outcome is attributable to two facts: (1) pancreatic cancers metastasize early, before clinical detection, and (2) current anti-cancer therapies are inadequate. Our laboratory tackles these problems by understanding how tumors metastasize and identifying vulnerabilities that will lead to better therapies. Our efforts include studies of the tumor microenvironment (including the immune microenvironment), metabolism, cellular plasticity and metastasis biology. We rely on genetically engineered mice that recapitulate salient features of the human disease, functional genomics, epigenetics, and in vitro culture methods that recapitulate the unique microenvironment of the tumor. In addition, we maintain a strong interest in liver plasticity and the pathogenesis of type I diabetes.
研究兴趣
论文共 337 篇作者统计合作学者相似作者
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Cancer Researchno. 6_Supplement (2024): 6627-6627
Mamta Gupta,Hoon Choi,Emma E. Furth, Miguel Joaquim,Stephen Pickup,Cynthia Clendenin, Margo Orlen,Thomas Karasic,Hee Kwon Song,Yong Fan, Peter O'Dwyer,Robert H. Vonderheide,
CANCER RESEARCHno. 2 (2024)
Laleh Abbassi, Jullien Dilly,Annan Yang,Giselle Uribe, Branden Parent,Connor Hennessey,Kevin Kapner,Alexander Jordan, Shatavisha Dasgupta, Micaela Morgado, Taimour Baslan,Li Qiang,
Urszula N. Wasko,Jingjing Jiang,Yingyun Wang,Lorenzo Tomassoni, Lingyan Jiang, Marie Menard,Alvaro Curiel-Garcia,Tanner C. Dalton, Margo Orlen,Cole Edwards,Clint Stalnecker,Julien Dilly,
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASEno. 1 (2024): 397-421
Brooke A Brown,Paul J Myers,Sara J Adair,Jason R Pitarresi,Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler,William Kane,Kyoung Eun Lee,
Cancer research (2024)
Nune Markosyan,Il-Kyu Kim, Charu Arora, Liz Quinones, Noah Cheng,Ben Z. Stanger,Robert H. Vonderheide
CANCER RESEARCHno. 2 (2024)
Roni Ben-Ami,Qiao-Li Wang,Jinming Zhang,Julianna G. Supplee,Johannes F. Fahrmann, Roni Lehmann-Werman,Lauren K. Brais, Jonathan Nowak,Chen Yuan,Maureen Loftus,Ana Babic,Ehsan Irajizad,
GUTno. 4 (2024): 639-648
Arnav Mehta,Lynn Bi, Deepika Yeramosu, Michael Bogaev, Martin Jankowiak, Abigail Collins, Aziz Al'Khafaji, Milan Parikh, Mehrtash Babadi, Kyle Evans,Alex Bloemendal, Russell Kunnes,
Cancer Researchno. 7_Supplement (2024)
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