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个人简介
Brendan Wren's research interests predominantly involve determining the genetic basis by which bacterial pathogens cause disease. His research group exploits a range of post genome research strategies to gain a comprehensive understanding of how these pathogens function, how they evolve and how they interact with their respective hosts.
A core interest includes studying glycosylation and glycostructures and how this relates to the survival and virulence of bacterial pathogens. An application of this basic research is the development of Protein Glycan Coupling Technology and other glycobiotechnological innovations for the production of recombinant glycoproteins. This has been applied for the development of inexpensive glycoconjugate vaccines for human and veterinary use.
研究兴趣
论文共 538 篇作者统计合作学者相似作者
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Ricardo Corona-Torres,Prerna Vohra,Cosmin Chintoan-Uta, Abi Bremner,Vanessa S. Terra,Marta Mauri, Jon Cuccui, Lonneke Vervelde,Brendan W. Wren,Mark P. Stevens
Sowmya Ajay Castro, Ian J Passmore,Didier Ndeh, Helen Alexandra Shaw,Alessandro Ruda,Keira Burns,Sarah Thomson,Rupa Nagar, Kathirvel Alagesan, Kieron Lucas,Sherif Abouelhadid,Mark Reglinski,
biorxiv(2024)
ACS infectious diseases (2023)
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Burhan Lehri, Georgina Navoly, Abigail Corser,Fauzy Nasher, Sam Willcocks,Pham Thi Ngoc,Brendan W. Wren,Luu Quynh Huong,Richard A Stabler
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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NPJ vaccinesno. 1 (2023): 48-10
Sherif Abouelhadid,Elizabeth R. Atkins,Emily J. Kay,Ian J. Passmore,Simon J. North, Burhan Lehri,Paul Hitchen, Eirik Bakke, Mohammed Rahman,Janine T. Bossé,Yanwen Li,Vanessa S. Terra,
biorxiv(2023)
ACS Infectious Diseasesno. 12 (2023): 2665-2674
Mark A. Harrison, Rebecca J. Farthing, Nyasha Allen,Lucy M. Ahern,Kristian Birchall, Michael Bond,Harparkash Kaur,Brendan W. Wren,Julien R. C. Bergeron,Lisa F. Dawson
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