He introduced accurate large-area soft lithography and later started the Advanced Thermal Packaging group in response to the needs of the industry for improved thermal interfaces and better miniaturized convective cooling. Important research topics are microtechnology / microfluidics for nature inspired miniaturized hierarchical supply networks, 3D packaging, and reduced thermal resistance to improve efficiency in future green datacenters and in sustainable energy conversion processes. His central focus is to make computer more efficient by miniaturization and volumetric densification and to help massively reduce the carbon footprint of the Information Industry. His Research is targeted to replace Moore’s law with a biologically inspired roadmap to reach the functional density and efficiency of our brain. As part of the recently started smart system Initiative he develops data driven medical technologies based on efficient, miniaturized cognitive wearables, edge, and cloud computers. The effort spans from new sensing principles to multi sensor data analytics and cognitive computing and brings sensing, computing, and artificial or augmented intelligence much closer to humans thereby making it much more valuable and useful.