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During his career spanning 37 years, he made major advances in the biosynthesis of naturally occurring drugs through studies of the molecular genetics and biochemistry of antibiotic production in microorganisms. Through work on the genetic manipulation of polyketide genes, his laboratory created novel metabolites, devised methods to purify and study polyketide synthase enzymes, established fermentation routes to pharmaceutically important compounds, and used genetic engineering to develop improved strains of commercially important microorganisms. He is particularly noted for combining biochemical, chemical, and genetic methods in his research. Dr. Hutchinson published over 240 papers, held numerous federal and industrial resea rch gra nts, and received many prestigious awards, including Guggenheim and Fullbright fellowships, the Charles Thom Research Achievement Award of the Society for Industrial Microbiology, the AACP Paul Dawson Biotechnology Award, the Research Achievement Award of the American Society for Pharmacognosy, and a Distinguished Alumni Award from Ohio State University.
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mag(2007)
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Evelyn Wendt-Pienkowski,Yong Huang, Jian Zhang,Bensheng Li, Hao Jiang,Hyungjin Kwon,C. Richard Hutchinson,Ben Shen
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