He is a co-author of the textbooks Resource Management in Real-time Systems and Networks (MIT Press, USA), Ad Hoc Wireless Networks: Architectures and Protocols (Prentice Hall, USA), WDM Optical Networks: Concepts, Design, and Algorithms (Prentice Hall, USA), An Analytical Approach to Optical Burst Switched Networks (Springer, USA), Parallel Computers: Architecture and Programming (Prentice-Hall of India, India), and New Parallel Algorithms for Direct Solution of Linear Equations (John Wiley & Sons, Inc., USA). His research interests include wireless networks, lightwave networks, real-time systems, and parallel and distributed computing. He has published a number of research papers in peer-reviewed international journals and refereed international conference proceedings in these areas.

Prof.Murthy is a co-recipient of Best Paper Awards from the 5th IEEE International Workshop on Parallel and Distributed Real-Time Systems (WPDRTS), 6th and also 11th IEEE Annual International Conference on High Performance Computing (HiPC), and 14th and also 19th IEEE International Conference on Networks (ICON). He has served as an Associate Editor of the IEEE Transactions on Computers and IEEE Transactions on Mobile Computing, and as a Subject Area Editor for the Journal of Parallel and Distributed Computing (JPDC) and INAE Letters (now Transactions of the Indian National Academy of Engineering). He is currently an Area Editor of Computer Networks (COMNET) Journal.