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Marijuana has been used by humans for more than 2,500 years as a medicinal agent and social drug. Cannabinoids are the chemicals in marijuana that are responsible for its effects on the body. A long-standing interest of our laboratory is the study of the mechanisms by which the cannabinoids affect the function of the brain. Delta-9-tetrahydrocannabinol (THC) is the cannabinoid in marijuana that is responsible for its mood- and sensation-altering effects. THC targets two receptors: the CB1 receptor present on neurons and the CB2 receptor that is present primarily on immune cells. Although THC targets these receptors when a person is exposed to the drug from the outside, we know that at least two “endogenous” (or, from the self) molecules also target these receptors. These two molecules are named the endocannabinoids. Our research focuses on the cannabinoids, the receptors with which they interact and the role of the endocannabinoids in brain function.
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论文共 353 篇作者统计合作学者相似作者
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Stefano Comai,Nicolas Nunez,Tobias Atkin,Maykel F. Ghabrash, Rita Zakarian,Allan Fielding,Marie Saint-Laurent,Nancy Low, Garrett Sauber,Eugenio Ragazzi,Cecilia J. Hillard,Gabriella Gobbi
bioRxiv : the preprint server for biology (2024)
Jennifer M. Knight, Edward Hackett,Aniko Szabo,Ruizhe Wu, Garrett Sauber,Bryon Johnson,Rachel N. Cusatis, Elizabeth Aughey,Steve W. Cole,Cecilia J. Hillard,Nirav N. Shah
Neuropsychopharmacologyno. 8 (2023): 1121-1132
Zoe Sirotiak, Brandon T. Gallagher,Courtney A. Smith-Hernandez,Lucas J. Showman,Cecilia J. Hillard,Angelique G. Brellenthin
PLOS ONEno. 12 (2023): e0291845-e0291845
Rachel Bollaert, Meghan Bennett,Kaley Davis,Cecilia Hillard, Jeffrey Whittle,Zeno Franco,Jacklynn Fitzgerald
ANNALS OF BEHAVIORAL MEDICINE (2023): S496-S496
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Neuropharmacology (2023): 109601-109601
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