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个人简介
My research concentrates on the biology of skeletal stem cells that are the basis for the high regenerative capacities of skeletal tissues and that are potentially deficient in various musculoskeletal diseases and disorders. I received continuous funding since 2005 from NIH, European Marie Curie Program and the French National Research Agency. The projects of my research team aim to elucidate the mechanisms of stem cell activation in their complex tissue environment in development, disease and repair employing genetic mouse models, genomics and cellular approaches. We focus on the periosteum, the tissue at the outer surface of bone and skeletal muscle adjacent to bone, that also plays essential roles in bone regeneration. The ATIP-AVENIR funding was key for us to accomplish the characterization skeletal stem cells within periosteum. These results are now the bases for several other projects further exploring periosteum functions in bone repair and its interactions with skeletal muscle, the vasculature and the nervous system.
研究兴趣
论文共 75 篇作者统计合作学者相似作者
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Yasmine Hachemi,Simon Perrin, Maria Ethel,Anais Julien, Julia Vettese, Blandine Geisler,Christian Göritz,Céline Colnot
bioRxiv the preprint server for biology (2024)
Simon Perrin, Cécile-Aurore Wotawa,Marine Luka,Fanny Coulpier,Cécile Masson,Mickaël M. Ménager,Céline Colnot
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Simon Perrin, Cécile-Aurore Wotawa, Vincent Bretegnier,Marine Luka,Fanny Coulpier,Cécile Masson,Mickael Ménager,Céline Colnot
biorxiv(2023)
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